12 documents found, page 1 of 2
Olive oil waste as a source of functional food ingredients: Assessing polypheno...
Ronca, Carolina L.; Marques, Sara S.; Ritieni, Alberto; Giménez-Martínez, Rafael; Barreiros, Luísa; Segundo, Marcela A.Around two million tons of olive oil are produced in Europe annually, with Portugal being among the top five European olive oil-producing countries. Olive oil production results in a substantial amount of waste in the form of olive leaves. These discarded olive leaves contain valuable phenolic compounds with antioxidant, anti-inflammatory, hypoglycaemic, neuroprotective, and antiproliferative properties. Due to...
Análise de resíduos de 5-fluorouracilo no exterior de bombas infusoras após rea...
Cardoso, Andreia; Barreiros, Luísa; Sá, Maria dos Anjos; Sousa, Eulália; Carvalho, Daniel; Correia, Patrícia; Moreira, FernandoPese embora os benefícios potenciais da administração infusional de 5-fluorouracilo (5-FU) em regime de domicílio, já existiram relatos de derrames e resíduos de 5-FU no exterior de bombas infusoras, que reforça a necessidade do desenvolvimento e aplicação de metodologia analítica que permita a sua deteção e quantificação (Chefchaouni et al., 2023).
Screening of antioxidant effect of spontaneous and bioinoculated with gluconoba...
Leitão, Mariana; Ferreira, Beatriz; Guedes, Beatriz; Moreira, Daniela; García, Pablo A.; Barreiros, Luísa; Correia, Patrícia Carla dos SantosFermented papaya is recognized as a nutraceutical with a diverse and rich composition. Fermentation of fruit with desirable microorganisms could be a strategy to improve the nutritional quality and profile of the fruit. Despite the popularity of fermented papaya, there is still a lack of knowledge on the effects of various fermentation parameters. The goal of this study was to screen the antioxidant and other p...
Screening of antioxidant activity of fermented papaya
Leitão, Mariana; Barreiros, Luísa; Moreira, Fernando; García, Pablo; Correia, PatríciaPapaya is the fruit of Carica papayaL., consumed for its beneficial proprieties, directlyor as a fermented fruitsupplement. Compare the total phenolic content (TPC) and the antioxidant activity (Ferric Reducing Antioxidant Power, FRAP) evolution in a variety of papaya fermentation experiments using fruit natural microorganisms (spontaneous fermentation) versus fermentation with Gluconobacter oxydansbioinoculati...
Fermented papaya: strategies to monitor and improve fermentation: preliminary s...
Leitao, Mariana; Ribeiro, Tatiana; Santos, Daniela; Moreira, Fernando; Barreiros, Luísa; García, Pablo; Correia, PatríciaIntroduction: Fermented papaya is known as a nutraceutical, with a unique composition and several health benefits. Its fermentation, being a central process of metabolism, converts the sugars in the fruit into alcohols or acids, with the intermediate formation of pyruvic acid. However, there is a lack of control and uniformity in terms of processes. Objectives: Carry out fermentation cycles of papaya in order t...
A importância dos probióticos nas cervejas artesanais: revisão narrativa
Santos, Diana; Pereira, Maria João; Moreira, Fernando; Barreiros, Luísa; Oliveira, Ana Isabel; Pinho, CláudiaA cerveja constitui uma bebida funcional dado o seu valor nutritivo e possível enriquecimento com ingredientes inovadores, que lhe confere propriedades nutricionais benéficas para a saúde do consumidor. Assim, os probióticos são ingredientes ativos passíveis de serem adicionados, pelas inúmeras vantagens na saúde do hospedeiro. Os alimentos funcionais contendo probióticos são geralmente produtos lácteos. Como t...
Benefits of fermented papaya in human health
Leitão, Mariana; Ribeiro, Tatiana; García, Pablo A.; Barreiros, Luísa; Correia, Patrícia Carla dos SantosFermented foods have been used for several years all over the world, due to their unique nutritional characteristics and because fermentation promotes conservation and food security. More over, fermented foods and beverages have a strong impact on human gut microbiota. Papaya is the fruit of the Carica papaya plant, traditionally used as a medicinal fruit, but there are also references to the use of the ferment...
Automatic and renewable micro-solid-phase extraction based on bead injection la...
Fernandes, Sara; Barreiros, Luísa; Sá, Paula; Miró, Manuel; Segundo, Marcela A.An automatic micro-solid-phase extraction (μSPE) method using on-line renewable sorbent beads followed by liquid chromatography–tandem mass spectrometry (LC–MS/MS) was established for the determination of tranexamic acid (TXA) in urine. The μSPE method was based on the bead injection (BI) concept combined with the mesofluidic lab-on-valve (LOV) platform. All steps of the μSPE–BI–LOV were implemented by computer...
Acetonitrile adducts of tranexamic acid as sensitive ions for quantification at...
Silva, Eduarda M. P.; Barreiros, Luísa; Fernandes, Sara R.; Sá, Paula; Ramalho, João P. Prates; Segundo, Marcela A.The quantitative analysis of pharmaceuticals in biomatrices by liquid chromatography coupled with electrospray ionization tandem mass spectrometry (LC-ESI-MS/MS) is often hampered by adduct formation. The use of the molecular ion resulting from solvent adducts for quantification is uncommon, even if formed in high abundance. In this work, we propose the use of a protonated acetonitrile adduct for the quantitati...
Noncovalent PEG Coating of Nanoparticle Drug Carriers Improves the Local Pharma...
Nunes, Rute; Araújo, Francisco; Barreiros, Luísa; Bártolo, Inês; Segundo, Marcela A.; Taveira, Nuno; Sarmento, Bruno; Neves, José DasAntiretroviral drug nanocarriers hold great promise for developing anti-human immunodeficiency virus (HIV) rectal microbicides. However, challenges remain, namely, concerning which properties are more suited for enhancing colorectal distribution and retention of microbicide compounds. In this work, we developed and assessed the in vitro and in vivo performance of poly(lactic-co-glycolic acid) (PLGA)-based nanop...