44 documents found, page 1 of 5
Contaminantes microbiológicos da cerveja artesanal: revisão narrativa
Santos, Diana; Barreiros, Luisa; Oliveira, Ana Isabel; Pinho, CláudiaEnquadramento: A autenticidade, inovação e qualidade associadas às cervejas artesanais tem contribuído para o aumento da produção e consumo desta bebida. Embora a cerveja artesanal apresente características que restringem o crescimento microbiano (ex: etanol, iso-α-ácidos, baixo pH), existem bactérias e leveduras capazes de tolerar estas condições e produzir alterações sensoriais, microbiológicas, químicas, e f...
Innovative pedagogical tools for parasitology based on interactive learning
Sequeira, Susie; Sousa, Mariana; Fernandes, Sara; Barreiros, Luísa; Cunha, Agostinho; Cruz, Agostinho; Fernandes, Sara; Barreiros, LuisaParasitic infections in children, in particular ectoparasitoses, remain a public health challenge within the school context in Portugal. As part of the curricular unit “Agentes e Vectores de Doença I” included in the first year of the Bachelor of Pharmacy, pedagogical tools have been developed to raise awareness on this issue among the various stakeholders involved in primary education. The developed activities...
Safeguarding patients, relatives, and nurses: A screening approach for detectin...
Cardoso, Andreia; Jesus, Ângelo; Barreiros, Luísa; Carvalho, Daniel; Sá, Maria dos Anjos; Carvalho, Susana; Correia, Patrícia; Moreira, FernandoThe leakage of 5-fluorouracil (5-FU) from elastomeric infusion pumps used in cancer therapy poses a potential risk of unintentional exposure to multiple individuals, including patients’ relatives and healthcare professionals, and may also compromise the accurate administration of 5-FU dosages to patients. This study aimed to develop, validate, and apply an analytical method to detect and quantify 5-FU residues ...
Fermented Papaya: Available formulations from online markets
Leitão, Mariana; Ribeiro, Tatiana; García, Pablo; Barreiros, Luísa; Correia, Patrícia; Barreiros, Luisa; Correia, Patrícia Carla dos Santos CorreiaFermentation is a process of central metabolism in which an organism converts a carbohydrate, such as starch or sugar, into an alcohol or an acid. Carica papaya, also known as papaya or pawpaw, belongs to the Caricaceae family and has four genera in the world. Due to papaya’s health benefits, this fruit is considered a valuable nutraceutical with an exceptionally diverse composition, encompassing vitamins and e...
Beer with probiotics: Benefits and challenges of their incorporation
Santos, Diana; Barreiros, Luisa; Jesus, Ângelo; Silva, Ana Luísa; Martins, João Paulo; Oliveira, Ana Isabel; Pinho, Cláudia; Jesus, ÂngeloBeer is considered one of the most consumed beverages worldwide and a potential vehicle for probiotics. However, there are several technical challenges to overcome during the production and storage of beers, as probiotics must remain viable until the moment of consumption. Therefore, this work aims to discuss how the incorporation of probiotics improves or adds value to beer and which variables influence the vi...
Lab-on-valve automated and miniaturized assessment of nanoparticle concentratio...
Marques, Sara S.; Ramos, Inês I.; Silva, Carla; Barreiros, Luisa; Domingues, Maria R.; Segundo, Marcela A.Nanoparticles (NPs) concentration directly impacts the dose delivered to target tissues by nanocarriers. The evaluation of this parameter is required during NPs developmental and quality control stages, for setting dose--response correlations and for evaluating the reproducibility of the manufacturing process. Still, faster and simpler procedures, dismissing skilled operators and post-analysis conversions are n...
Lab-on-valve automated and miniaturized assessment of nanoparticle concentratio...
Marques, Sara S.; Ramos, Inês I.; Silva, Carla; Barreiros, Luisa; Domingues, Maria R.; Segundo, Marcela A.Nanoparticles (NPs) concentration directly impacts the dose delivered to target tissues by nanocarriers. The evaluation of this parameter is required during NPs developmental and quality control stages, for setting dose−response correlations and for evaluating the reproduci bility of the manufacturing process. Still, faster and simpler procedures, dismissing skilled operators and post-analysis conversions are n...
Exploiting kinetic features of ORAC assay for evaluation of radical scavenging ...
Carvalho, Joana R. B.; Meireles, Andreia N.; Marques, Sara S.; Gregório, Bruno J. R.; Ramos, Inês I.; Silva, Eduarda M. P.; Barreiros, LuisaThe analysis and interpretation of data retrieved from Oxygen Radical Absorbance Capacity (ORAC) assays represent a challenging task. ORAC indexes originate from different mathematical approaches often lacking correct elucidation of kinetic features concerning radical scavenging reactions by antioxidant compounds. In this work, the expression of ORAC values as area under fluorescein (FL) decay curves (AUC) and ...
Rapid and sustainable HPLC method for the determination of uremic toxins in hum...
Silva, Luís A. P. ; Campagnolo, Stefano ; Fernandes, Sara R. ; Marques, Sara S. ; Barreiros, Luisa; Sampaio‑Maia, Benedita ; Segundo, Marcela A.Protein-bound uremic toxins, mainly indoxyl sulfate (3-INDS), p-cresol sulfate (pCS), and indole-3-acetic acid (3-IAA) but also phenol (Pol) and p-cresol (pC), are progressively accumulated during chronic kidney disease (CKD). Their accurate measurement in biomatrices is demanded for timely diagnosis and adoption of appropriate therapeutic measures. Multiana lyte methods allowing the establishment of a uremic m...
Sample preparation and chromatographic methods for the determination of protein...
Fernandes, Sara R.; Meireles, Andreia N.; Marques, Sara S.; Silva, Luís; Barreiros, Luisa; Sampaio-Maia, Benedita; Miro, Manuel; Segundo, Marcela A.Protein-bound uremic retention solutes, such as indole-3-acetic acid, indoxyl sulfate, p-cresol and p-cresol sulfate, are associated with the development of several pathologies, namely renal, cardiovascular, and bone toxicities, due to their potential accumulation in the human body, thus requiring analytical methods for monitoring and evaluation. The present review addresses conventional and advanced sample tre...