7 documents found, page 1 of 1

Congenital Central Hypoventilation Syndrome: The Singularity of A Successful Case

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Frequency of Th1 and Th17 Cells and IL‐17A Levels in Peripheral Blood and Perit...

Introduction: Chronic kidney disease is characterized by an immune imbalance. In peritoneal dialysis (PD), chronic expo‐ sure to high‐load glucose solutions may further aggravate such disturbances. Among these inflammatory mediators, T helper 1 (Th1) and Th17 cells as well as interleukin 17A (IL‐17A) seem to stand out. We aimed to quantify the frequency of Th1 and Th17 cell subsets and IL‐17A levels in blood an...

Real-world challenges in first-line treatment of metastatic EGFR-mutated non-sm...

Osimertinib, a third-generation tyrosine kinase inhibitor (TKI), was recently introduced in several countries, including Portugal (reimbursement in 2021), as first-line treatment for patients with locally advanced or metastatic non-small cell lung cancer (NSCLC) with activating proto-oncogene epidermal growth factor receptor mutations (EGFRm), after showing significant efficacy and safety when used in patients ...

Epipericardial fat necrosis in chest CT and MRI: a case report of an unusual ca...

Background: Epipericardial fat necrosis (EFN) is a benign and self-limited condition of unknown cause with a good prognosis, usually affecting otherwise healthy patients. Clinically, it presents with severe acute left pleuritic chest pain, often leading the patient to the Emergency Room (ER). Case presentation: A 23-year-old male, smoker (5 pack-years), was evaluated in the ER due to left pleuritic chest pain, ...

Real-world challenges in first-line treatment of metastatic EGFR-mutated non-sm...

Maculopapular cutaneous Mastocytosis

Mastocytosis is a rare disorder caused by proliferation and accumulation of mast cells in various tissues, with characteristic symptoms associated with the release of their mediators. Its cutaneous form, usually benign, is the most frequent among children. The authors report the case of a two-month-old male infant who presented to the Emergency Department with small, tan-to-brown macules and papules distributed...

Maculopapular cutaneous Mastocytosis

Mastocytosis is a rare disorder caused by proliferation and accumulation of mast cells in various tissues, with characteristic symptoms associated with the release of their mediators. Its cutaneous form, usually benign, is the most frequent among children. The authors report the case of a two-month-old male infant who presented to the Emergency Department with small, tan-to-brown macules and papules distributed...