5 documents found, page 1 of 1
Fertility optimization in women with cancer: from preservation to contraception
Barreto, Jorge
Genotypic resistance profiles of HIV-2 infected patients from Cape Verde failin...
Moranguinho, Inês; Borrego, Pedro; Gonçalves, Fátima; Gomes, Perpétua; Rocha, José; Barreto, Jorge; Taveira, NunoThe pol gene from HIV-2 infected patients from Cape Verde experiencing virologic failure was sequenced and drug resistance mutations were determined. Most patients were taking a first line regimen of AZT, 3TC and LPV/r. Resistance mutations were found in most patients (11/17, 64.7%) especially I82F (4/7, 57.1%) and M184 V (10/17, 58.8%). Resistance to all reverse transcriptase and protease inhibitors was found ...
Assessment of the Cavidi ExaVir load assay for monitoring plasma viral load in ...
Borrego, Pedro; Gonçalves, Maria Fátima; Gomes, Perpétua; Araújo, Lavínia; Moranguinho, Inês; Figueiredo, Inês Brito; Barahona, Isabel; Rocha, JoséHIV plasma viral load is an established marker of disease progression and of response to antiretroviral therapy, but currently there is no commercial assay validated for the quantification of viral load in HIV-2-infected individuals. We sought to make the first clinical evaluation of Cavidi ExaVir Load (version 3) in HIV-2- infected patients. Samples were collected from a total of 102 individuals living in Cape...
Assessment of the Cavidi ExaVir Load Assay for Monitoring Plasma Viral Load in ...
Borrego, Pedro; Gonçalves, Maria Fátima; Gomes, Perpétua; Araújo, Lavínia; Moranguinho, Inês; Figueiredo, Inês Brito; Barahona, Isabel; Rocha, JoséHIV plasma viral load is an established marker of disease progression and of response to antiretroviral therapy, but currently there is no commercial assay validated for the quantification of viral load in HIV-2-infected individuals. We sought to make the first clinical evaluation of Cavidi ExaVir Load (version 3) in HIV-2- infected patients. Samples were collected from a total of 102 individuals living in Cape...
Genetic diversity and drug resistance profiles in HIV type 1- and HIV type 2-in...
Oliveira, Vânia; Bártolo, Inês; Borrego, Pedro; Rocha, Cheila; Valadas, Emília; Barreto, Jorge; Almeida, Elsa; Antunes, Francisco; Taveira, NunoOur aim was to characterize for the first time the genetic diversity of HIV in Cape Verde Islands as well as the drug resistance profiles in treated and untreated patients. Blood specimens were collected from 41 HIV-1 and 14 HIV-2 patients living in Santiago Island. Half of the patients were on antiretroviral treatment (ART). Pol and env gene sequences were obtained using in-house methods. Phylogenetic analysis...