4 documents found, page 1 of 1
Efeito cicatrizante do (-)-borneol incorporado ao filme bioativo de quitosana e...
Barreto, Rosana de Souza SiqueiraCoordenação de Aperfeiçoamento de Pessoal de Nível Superior; Medicinal plants and their constituents have been shown to be a major source of new biomolecules. The (-)-borneol is an alcohol monoterpene which shows a series of biological activities with potential to accelerate the wound healing process. The present study was to conduct a systematic review that provides an overview of the characteristics of monote...
Anti-inflammatory and redox-protective activities of citronellal
Melo, Mônica Santos de; Guimarães, Adriana Gibara; Santana, Michele Fraga de; Barreto, Rosana de Souza Siqueira; Lima, Amanda do Carmo Bion deThe anti-inflammatory and redox protective effects of the citronellal (CT) were evaluated using in vivo and in vitro tests. Intraperitoneal (i.p.) administration of CT (50, 100, and 200 mg/kg) inhibited (p < 0.05) the carrageenan-induced leukocyte migration to the peritoneal cavity. Additionally, the carrageenan- and arachidonic acid-induced rat hind paw edema was significantly inhibited (p < 0.05) by i.p. admi...
Bioassay-guided evaluation of central nervous system effects of citronellal in ...
Melo, Mônica Santos de; Souza, Marilia Trindade de Santana; Guimarães, Adriana Gibara; Barreto, Rosana de Souza SiqueiraThe central nervous system (CNS) depressant and anticonvulsant activities of citronellal (CT) were investigated in animal models. The CT in doses of 100, 200 and 400 mg/kg injected by i.p. route in mice caused a significant decrease in the motor activity of animals when compared with the control group. The highest dose of CT significantly reduced the remaining time of the animals on the Rota-rod apparatus up to...
Volatile constituents and behavioral change induced by Cymbopogon winterianus l...
Leite, Bárbara Lima Simioni; Souza, Thaís Teles de; Antoniolli, Ângelo Roberto; Guimarães, Adriana Gibara; Barreto, Rosana de Souza SiqueiraCymbopogon winterianus Jowitt (‘Java citronella’) is an important essential oil yielding aromatic grass cultivated in India and Brazil and its volatile essential oils extracted from its leaves are used in perfumery, cosmetics, pharmaceuticals and flavoring industries. However, there is no report on any psychopharmacological study of C. winterianus leaf essential oil (LEO) available to date. In this study, the p...