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Management of ibrutinib treatment in patients with B-cell malignancies: clinica...

Carda, JP; Santos, L; Mariz, JM; Monteiro, P; Gonçalves, HM; Raposo, J; Silva, MG

Objectives: Ibrutinib, a potent inhibitor of the Bruton tyrosine kinase, has revolutionized the treatment of many B-cell malignancies. Ibrutinib has an established favorable toxicity profile with up to 8 years of experience in clinical trials; however, despite ibrutinib’s favorable toxicity profile, dose reductions and treatment discontinuations are becoming more evident in clinical practice, particularly in th...

Date: 2021   |   Origin: Repositório Aberto da Universidade do Porto
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