2 documents found, page 1 of 1
The SIGMA rat brain templates and atlases for multimodal MRI data analysis and ...
Barrière, D. A.; Magalhães, R.; Novais, A.; Marques, P.; Selingue, E.; Geffroy, F.; Marques, F.; Cerqueira, J.; Sousa, J. C.; Boumezbeur, F.Preclinical imaging studies offer a unique access to the rat brain, allowing investigations that go beyond what is possible in human studies. Unfortunately, these techniques still suffer from a lack of dedicated and standardized neuroimaging tools, namely brain templates and descriptive atlases. Here, we present two rat brain MRI templates and their associated gray matter, white matter and cerebrospinal fluid p...
The dynamics of stress: a longitudinal MRI study of rat brain structure and con...
Magalhães, Ricardo José Silva; Barrière, D. A.; Novais, Ashley Cruz; Marques, Fernanda; Marques, Paulo César Gonçalves; Cerqueira, João JoséStress is a well-established trigger for a number of neuropsychiatric disorders, as it alters both structure and function of several brain regions and its networks. Herein, we conduct a longitudinal neuroimaging study to assess how a chronic unpredictable stress protocol impacts the structure of the rat brain and its functional connectome in both high and low responders to stress. Our results reveal the changes...