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Study on the antineoplastic and toxicological effects of pomegranate (Punica gr...

Yu, Manyou; Gouvinhas, Irene; Pires, Maria J.; Neuparth, Maria J.; Costa, Rui M. Gil da; Medeiros, Rui; Bastos, Margarida M.S.M.; Vala, Helena

Punica granatum L. (pomegranate) has been used in functional foods due to its various health benefits. However, the in vivo biological potential of its leaf remains little known. This study has aimed to characterize the antineoplastic and toxicological properties of using pomegranate leaf infusion (PLI) on transgenic mice carrying human papillomavirus (HPV) type 16 oncogenes. Thirty-eight mice were divided into...


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