32 documents found, page 1 of 4

Urocortin-2 as a novel biomarker of patient outcomes in HFpEF: A prospective co...

Diagnostic and monitoring applications using Near infrared (NIR) Spectroscopy i...

Early cancer diagnosis plays a critical role in improving treatment outcomes and increasing survival rates for certain cancers. NIR spectroscopy offers a rapid and cost-effective approach to evaluate the optical properties of tissues at the microvessel level and provides valuable molecular insights. The integration of NIR spectroscopy with advanced data-driven algorithms in portable instruments has made it a cu...

Acute Kidney Injury after Coronary Artery Bypass Graft Surgery: The heterogenei...

Introduction: Meta-analysis is the method to pool data from studies that report the same event in a comparable sample and, thus, summarize information from different populations. However, data extraction is limited to the information provided in the included studies. Frequently, individual patient information is not available, hence, real world data access is limited. Individual patient data (IPD) meta-analysis...

Comparing one sample’s observed survival with the expected in the general popul...

EARLY AND MIDTERM OUTCOMES FOLLOWING AORTIC VALVE REPLACEMENT WITH MECHANICAL V...

Objectives: To compare 7-year survival and freedom from reoperation, as well as early clinical and hemodynamic outcomes, after surgical aortic valve replacement (SAVR) with mechanical or bioprosthetic valves in patients aged 50-70 years. Methods: single-center retrospective cohort study including adults aged 50-70 years who underwent SAVR in 2012 with a mechanical or bioprosthetic valve. Median follow-up was 7 ...

Influence of EPICardial adipose tissue in HEART diseases (EPICHEART) study: Pro...

Accumulation of epicardial adipose tissue (EAT) is associated with coronary artery disease (CAD) and increased risk of coronary events in asymptomatic subjects and low-risk patients, suggesting that EAT promotes atherosclerosis in its early stage. Recent studies have shown that the presence of CAD affects the properties of adjacent EAT, leading to dynamic changes in the molecular players involved in the interpl...

Reconstructing survival data from published Kaplan-Meier curves: an algorithm v...

Background: The number of health-related publications has been exponential in the recent decade. Indeed, cardiovascular area includes more than 670k papers published at MEDLINE [((cardiovascular) NOT ((("Animals"[Mesh] NOT ("Animals"[Mesh] AND "Humans"[Mesh])))], of which, more than 20k are related to coronary artery bypass grafting (CABG). We are witnessing a 6% increase in publications per year. The growth in...

Quinones as Strecker degradation reagents in wine oxidation processes

The Strecker aldehydes formed during the reaction between α-amino acids (phenylalanine or methionine) and either gallic acid, caffeic acid or (+)-catechin ortho-quinones were evaluated in wine-model systems. It was demonstrated that phenylacetaldehyde was formed by quinone intermediates at wine pH. The highest amounts of phenylacetaldehyde during the 10days of experiment (69±5µg/L/day; 7x>Control) were obtained...

Characterization of 2,3-diarylxanthones by electrospray mass spectrometry: gas-...

Xanthones (XH) are a class of heterocyclic compounds widely distributed in nature that hold numerous noteworthy biological and antioxidant activities. Therefore, it is of utmost importance to achieve relevant detailed structural information to understand and assist prediction of their biological properties. The potential relationship between radical-mediated xanthone chemistry in the gas phase and their promisi...

Quantification of 3-deoxyglucosone (3DG) as an aging marker in natural and forc...

The Maillard reaction product 3-deoxyglucosone (3DG) was quantified in wines, by high-performance liquid chromatography-mass spectrometry analysis after derivatization with ortho-phenylenediamine. Both sweet red Port wines and dry white wines were analysed during natural and forced aging. In natural aging, and for dry white wines, 3DG is negatively correlated to age (r = −0.939), while for sweet red Port wines,...