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A case of equine multicentric lymphoma: Clinical, microscopical, and molecular ...

Silva, GF; Ribeiro, TE; Cunha, R; Salas, PB; Guimarães, T; Ribeiro, MR; Barros, G; Carvalho, F; Mesquita, JR; Amorim, I

Background: Although relatively uncommon, lymphoma is the most prevalent haematopoietic neoplasia in horses, and multicentric lymphoma remains the most common presentation of the disease. The pathogenesis of equine lymphoma is still poorly understood and the diagnosis is usually confirmed at an advanced stage of the disease, compromising the prognosis. This study investigated the clinical, pathological, and mol...


Assessment of benzoquinones and mycotoxins in cereal flour samples from Portuga...

Alvito, Paula; Hilário, C; Barros, G; Duarte, S; Pires, M.J.; Magro, A; Assunção, R.; Ferreira, RB; Carvalho, MO

One of the most relevant problems in stored grain is the contamination by insects and mycotoxin-producing fungi. The red flour beetle, Tribolium castaneum (Herbst) (Coleoptera, Tenebrionidae), one of the major key-pests of milled grain, is resistant to Beauveria bassiana infection, producing benzoquinone-containing defensive secretions, that reduce fungal germination and growth. It can be affirmed that the tene...


Genomic imbalances defining novel intellectual disability associated loci

Lopes, F; Torres, F; Soares, G; Barbosa, M; Silva, J; Duque, F; Rocha, M; Sá, J; Oliveira, G; Sá, MJ; Temudo, T; Sousa, S; Marques, C; Lopes, S

Background: High resolution genome-wide copy number analysis, routinely used in clinical diagnosis for several years, retrieves new and extremely rare copy number variations (CNVs) that provide novel candidate genes contributing to disease etiology. The aim of this work was to identify novel genetic causes of neurodevelopmental disease, inferred from CNVs detected by array comparative hybridization (aCGH), in a...



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