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Irisin: An anti-inflammatory exerkine in aging and redox-mediated comorbidities

Trettel, Caio Dos Santos; Pelozin, Bruno Rocha de Avila; Barros, Marcelo Paes; Bachi, André Luis Lacerda; Braga, Pedro Gabriel Senger

Human beings lead largely sedentary lives. From an evolutionary perspective, such lifestyle is not beneficial to health. Exercise can promote many enabling pathways, particularly through circulating exerkines, to optimize individual health and quality of life. Such benefits might explain the protective effects of exercise against aging and noncommunicable diseases. Nevertheless, the miRNA-mediated molecular mec...


Combined Chair-Based Exercises Improve Functional Fitness, Mental Well-Being, S...

Furtado, Guilherme Eustáquio; Letieri, Rubens Vinícius; Caldo-Silva, Adriana; Trombeta, Joice C. S.; Monteiro, Clara; Rodrigues, Rafael Nogueira

Regular exercise has long been shown to positively impact the immune system responsiveness and improve mental well-being (MWB). However, the putative links between biomarkers of mental health and immune efficiency in exercising subjects have been scarcely investigated. The aim of this study was to verify the effect of a 14-week combined chair-based exercise program (CEP) on salivary steroid hormones and anti-mi...


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