32 documents found, page 1 of 4
Comprehensive histopathological analysis of gastric cancer in European and Lati...
Martínez-Ciarpaglini, C; Barros, R; Caballero, C; Boggino, H; Alarcón-Molero, L; Peleteiro, B; Ruiz-García, E; Fernandez-Figueroa, E"Introduction: Gastric cancer (GC) burden is currently evolving with regional differences associated with complex behavioural, environmental, and genetic risk factors. The LEGACy study is a Horizon 2020-funded multi-institutional research project conducted prospectively to provide comprehensive data on the tumour biological characteristics of gastroesophageal cancer from European and LATAM countries. Material a...
Effects of Time-Restricted Eating on Body Composition, Biomarkers of Metabolism...
Lages, M; Carmo-Silva, S; Barros, R; Guarino, MPObesity is a chronic, complex and multi-factorial condition with an increasing prevalence worldwide. Irregular eating schedules might be a contributing factor to these numbers through the dysregulation of the circadian system. Time-restricted eating (TRE), an approach that limits eating windows, has been studied as a strategy to treat obesity, aligning eating occasions with metabolic circadian rhythms. This rev...
Mediterranean Diet-Based Sustainable Healthy Diet and Multicomponent Training C...
Sampaio, J; Pizarro, A; Pinto, J; Oliveira, B; Moreira, A; Padrão, P; Guedes de Pinho, P; Moreira, P; Barros, R; Carvalho, J"Background: Diet and exercise interventions have been associated with improved body composition and physical fitness. However, evidence regarding their combined effects in older adults is scarce. This study aimed to investigate the impact of a combined 12-week Mediterranean diet-based sustainable healthy diet (SHD) and multicomponent training (MT) intervention on body composition, anthropometry, and physical f...
Combined mediterranean diet-based sustainable healthy diet and multicomponent t...
Sampaio, J; Pinto, J; Pizarro, A; Oliveira, B; Moreira, A; Padrão, P; Moreira, P; Guedes de Pinho, P; Carvalho, J; Barros, RBackground and aims: Healthy dietary patterns and exercise practices have been associated with improved metabolic and inflammatory profiles. However, studies regarding the combined effect of these interventions on plasma biomarkers and metabolome in older adults are sparser. The primary aim of this study was to investigate the impact of a combined Mediterranean Diet-based Sustainable Healthy Diet (SHD) and Mult...
Valorisation of red beet waste: one-step extraction and separation of betalains...
Rosa, ME; Ferreira, AM; Neves, CMSS; Almeida, MT; Barros, R; Cristovão, AC; Sousa, Ana Catarina; Reis, PM; Rebelo, LPN; Esperança, JMSS; Coutinho, JAPGlobally, up to 50% of root crops, fruits and vegetables produced is wasted. Beetroot stems and leaves fit into this scenario, with only a small fraction being used in cattle food. One way of approaching this problem is through their valorisation, by extracting and recovering valuable compounds present in this type of waste that could be used in other applications, while contributing towards a circular economy....
Does the Mediterranean Dietary Pattern Promote Lower Sodium Urinary Excretion i...
Rodrigues, M; Castro Mendes, F; Padrão, P; Delgado, L; Barros, R; Cavaleiro Rufo, J; Silva, D; Moreira, A; Moreira, PAn adequate sodium intake is related to various health benefits. Parallelly, the Mediterranean diet (MD) is a dietary pattern known for its many positive impacts on health. Nonetheless, the association between adherence to the MD and sodium urinary excretion is scarce, even more in children. This study aimed to assess the association between MD adherence and the excretion of sodium, as a proxy of intake. This c...
Sharing biomedical data: Strengthening ai development in healthcare
Pereira, T; Morgado, J; Silva, F; Pelter, MM; Dias, VR; Barros, R; Freitas, C; Negrão, E; Lima, BF; Silva, MC; Madureira, AJ; Ramos, I; Hespanhol, VArtificial intelligence (AI)-based solutions have revolutionized our world, using extensive datasets and computational resources to create automatic tools for complex tasks that, until now, have been performed by humans. Massive data is a fundamental aspect of the most powerful AI-based algorithms. However, for AI-based healthcare solutions, there are several socioeconomic, technical/infrastructural, and most i...
Prognostic significance of MUC2, CDX2 and SOX2 in stage II colorectal cancer pa...
Ribeirinho-Soares, S; Pádua, D; Amaral, AL; Valentini, E; Azevedo, D; Marques, C; Barros, R; Macedo, F; Mesquita, P; Almeida, RBackground: Colorectal cancer (CRC) remains a serious health concern worldwide. Despite advances in diagnosis and treatment, about 15 to 30% of stage II CRC patients subjected to tumor resection with curative intent, develop disease relapse. Moreover, the therapeutic strategy adopted after surgery is not consensual for these patients. This supports the imperative need to find new prognostic and predictive bioma...
Proteomics analysis of gastric cancer patients with diabetes mellitus
Osorio, H; Silva, C; Ferreira, M; Gullo, I; Máximo, V; Barros, R; Mendonça, F; Oliveira, C; Carneiro, FProteomics is a powerful approach to study the molecular mechanisms of cancer. In this study, we aim to characterize the proteomic profile of gastric cancer (GC) in patients with diabetes mellitus (DM) type 2. Forty GC tissue samples including 19 cases from diabetic patients and 21 cases from individuals without diabetes (control group) were selected for the proteomics analysis. Gastric tissues were processed f...
Gloeothece sp.—exploiting a new source of antioxidant, anti-inflammatory, and a...
Amaro, HM; Barros, R; Tavares, T; Almeida, R; Pinto, IS; Malcata, FX; Guedes, ACBioactive lipidic compounds of microalgae, such as polyunsaturated fatty acids (PUFA) and carotenoids, can avoid or treat oxidation-associated conditions and diseases like inflammation or cancer. This study aimed to assess the bioactive potential of lipidic extracts obtained from Gloeothece sp.–using Generally Recognized as Safe (GRAS) solvents like ethanol, acetone, hexane:isopropanol (3:2) (HI) and ethyl lact...