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Tandem Thio-Michael Addition/Remote Lactone Activation of 5-Hydroxymethylfurfur...
Rafael, Rafael F.; Ravasco, Joao M.J.M.; Andrade, Késsia H.S.; Coelho, Jaime A.S.; Moreira, Rui; Oliveira, Rafael; Nogueira, Fátima; Afonso, Carlos A.M.Funding Information: We thank the Fundação para a Ciência e a Tecnologia (SFRH/BD/120829/2016, SFRH/BD/148211/2019, UIDB/04138/2020, UIDP/04138/2020, PTDC/QUI‐QOR/32008/2017 and GHTM‐UID/04413/2020). The project leading to this application has received funding from the European Union's Horizon 2020 research and innovation programme under grant agreement No 951996. J. A. S. C. thanks the Fundação para a Ciência ...
Indole-Containing Pyrazino[2,1-b]quinazoline-3,6-diones Active against Plasmodi...
Long, Solida; Duarte, Denise; Carvalho, Carla; Oliveira, Rafael; Santarém, Nuno; Palmeira, Andreia; Resende, Diana I. S. P.; Silva, Artur M. S.Funding Information: This research was supported by national funds through FCT-Foundation for Science and Technology within the scope of UIDB/04423/2020, UIDP/04423/2020, IUD/04413/2020 and under the project PTDC/SAU-PUB/287336/2017 (reference POCI-01-0145-FEDER-028736), cofinanced by COMPETE 2020, Portugal 2020 and the European Union through the ERDF and by FCT through national funds, as well as CHIRALBIOACTIV...
Prevalence of pfk13 and pfmdr1 polymorphisms in Bounkiling, Southern Senegal
Ahouidi, Ambroise; Oliveira, Rafael; Lobo, Lis; Diedhiou, Cyrille; Mboup, Souleymane; Nogueira, FatimaBACKGROUND: Delayed Plasmodium falciparum parasite clearance has been associated with Single Nucleotide Polymorphisms (SNPs) in the kelch protein propeller domain (coded by pfk13 gene). SNPs in the Plasmodium falciparum multidrug resistance gene 1 (pfmdr1) are associated with multi-drug resistance including the combination artemether-lumefantrine. To our knowledge, this is the first work providing information o...