Neste trabalho, foram desenvolvidos dois genossensores eletroquímicos descartáveis para a identificação de plantas baseado na reação de hibridização entre duas cadeias de ADN complementares de duas espécies de plantas: Erica arborea (urze) e Castanea sativa (castanheiro). Analisando bases de dados públicas, foram selecionados dois pares de sequências especificamente cortadas e desenhadas para identificar o ADN ...
P-glycoprotein (P-GP) is a transporter molecule expressed on the apical surface of capillary endothelial cells of the Blood–Brain Barrier (BBB), whose activity heavily influences drug distribution, including antidepressants. This transporter is encoded by ABCB1 gene, and genetic variations within ABCB1 gene have been proposed to affect drug efflux and have been previously associated with depression. In this con...
Medicinal plants have been traditionally used throughout time as therapeutic treatments. These plants possess different compounds with antioxidant, anti-inflammatory and antimicrobial properties of industrial interest. In particular, the plants Achillea millefolium L., Arnica montana L., Calendula of icinalis L., Chamaemelum nobile L. All. and Taraxacum of icinale F.H. Wigg. belonging to the Asteraceae family, ...
The increasing demand for nutraceuticals in the circular economy era has driven the research toward studying bioactive compounds from renewable underexploited resources. In this regard, the exploration of brown algae has shown significant growth and maintains a great promise for the future. One possible explanation could be that brown algae are rich sources of nutritional compounds (polyunsaturated fatty acids,...