13 documents found, page 1 of 2
Creatinine Clearance in Acute Brain Injury: A Comparison of Methods
Monteiro, E; Pereira, MF; Barroso, I; Dias, CC; Czosnyka, M; Paiva, JA; Dias, CBackgroundCurrently, the measurement of glomerular filtration rate is very complex and costly, so its daily evaluation is performed using endogenous markers, of which creatinine is the most frequently used. It allows the estimation of glomerular filtration rate by means of its clearance or by formulas based on its serum and urine concentration. Augmented renal clearance (ARC) is frequent among critically ill pa...
White blood cells in a healthy adolescent population according to social and he...
Barroso, I; Ramos, E; Craveiro, V; Guimarães, JTBackground:The immune system constitutes a sensory system both for heritable and non-heritable factors. Among the latter, social and environmental determinants of health may influence and shape the immune system in early life. To study the relationship between leukocytes and determinants of health in adolescence, we assessed total and differential white blood cells (WBC) according to social and environmental de...
The prognostic impact of magnesium in acute heart failure is different accordin...
Cidade-Rodrigues, C; Cunha, FM; Elias, C; Carreira, M; Barroso, I; Bettencourt, P; Lourenço, PBackground: Hypermagnesemia predicts mortality in chronic heart failure (HF); however, in acute HF, magnesium does not seem to be outcome-associated. Diabetes mellitus (DM) frequently associates with altered magnesium status. We hypothesized that DM might influence the prognostic impact of magnesium in acute HF. Methods: This is a retrospective cohort study of hospitalized patients with acute HF. Patients witho...
How the metabolic phenotype in adulthood is affected by long-lasting immunologi...
Barroso, I; Guimarães, JT; Craveiro, V; Severo, M; Ramos, EA close relationship between immune and metabolic systems has been perceived in the recent past. We aimed to assess whether the immunological trajectories of circulating white blood cells (WBC) started in adolescence, affects the metabolic phenotype in adulthood. We used data from 1183 participants of the population-based EPITeen cohort, evaluated at 13, 17, 21, 24 and 27 years of age. The Immunological traject...
Pericardial NT-Pro-BNP and GDF-15 as Biomarkers of Atrial Fibrillation and Atri...
Fragão-Marques, M; Barroso, I; Farinha, R; Miranda, IM; Martins, D; Mancio, J; Rocha-Neves, J; Guimarães, JT; Leite-Moreira, A; Falcão-Pires, IAims: This study aimed to evaluate the association of GDF-15 and NT-pro-BNP in two different biological matrices with AF in severe aortic stenosis patients undergoing aortic valve replacement surgery (AVR), its association with atrial matrix remodeling, as well as with 30-day postoperative outcomes. Main Methods: One hundred and twenty-six patients between 2009 and 2019 with severe aortic stenosis undergoing AV...
Immunological Trajectories of White Blood Cells from Adolescence to Adulthood: ...
Barroso, I; Guimarães, JT; Severo, M; Craveiro, V; Ramos, EBackground: The immune system gradually matures early in life in the face of internal and external stimuli. Whether the immune responses are lasting and stable during the course of life is still unclear. Methods: As part of the EPITeen cohort, 1183 adolescents were prospectively evaluated at the ages of 13, 17, 21, 24 and 27. Sociodemographic, behavioral and clinical data were collected by self- and face-to-fac...
Gut microbiota changes after metabolic surgery in adult diabetic patients with ...
Eva Lau Gouveia; Belda, E; Picq, P; Carvalho, Davide; Ferreira Magalhães, M; Silva, MM; Barroso, I; Correia, Flora; pina-vaz, c; Miranda, IBackground: Roux-en-Y gastric bypass (RYGB) surgery is one of the most efficient procedures for the treatment of obesity, also improving metabolic and inflammatory status, in patients with mild obesity. The underlying mechanisms have not been fully understood, but gut microbiota is hypothesized to play a key role. Our aim was to evaluate the association between gut microbiota changes and anthropometric, metabol...
Dynamics of growth differentiation factor 15 in acute heart failure
Lourenço, P; Cunha, FM; Ferreira-Coimbra, J; Barroso, I; Guimarães, JT; Bettencourt, PAims: Risk stratification in acute heart failure (HF) patients can help to decide therapies and time for discharge. The potential of growth differentiation factor 15 (GDF-15) in HF has been previously shown. We aimed to study the importance of GDF-15-level variations in acute HF patients. Methods and results: We retrospectively evaluated a cohort of patients hospitalized due to acute HF. GDF-15 was measured bot...
Inflammatory response assessment in patients with COVID-19 under extracorporeal...
Fragão-Marques, M; Barroso, I; Loureiro, H; Duarte-Gamas, L; Pinheiro, D; Guimarães, JT"Background: Extracorporeal membrane oxygenation (ECMO), could be extremely helpful in the management of COVID-19 patients with refractory hypoxemic respiratory failure; however, to date, evidence on the true effecttiveness of ECMO in the COVID19 setting still hangs in the balance. Methods: This was a prospective cohort study of 39 COVID-19 patients admitted to the intensive care unit (ICU) in an experienced EC...
Parental education associated with immune function in adolescence
Barroso, I; Cabral, M; Ramos, E; Guimarães, JTBackground: The immune system is affected and shaped by several internal and external factors. Among the external variables, the socioeconomic status is known to influence the immune system since the early years of life and throughout life. Methods: In this study, we assessed the relationship between parental education with the white blood cells and its subtypes in 1213 adolescents from the EPITeen cohort, asse...