93 documents found, page 1 of 10
Detecting Candida spp. through an innovative genosensor
Castanheira, Michelle; Morais, Stephanie; Lima, Luís; Santos, Marlene; Barroso, M. Fátima; Santos, MarleneCandida spp. is the second most common cause of invasive fungal infection in hematopoietic stem cell transplantation (HSCT) patients and are associated with high mortality rates, ranging from 40 to 90%. Timely and accurate diagnosis is crucial for successful HSCT treatment. Current diagnostic methods, relying on conventional approaches, have limitations. Molecular and serological tests, although accurate, are t...
Improving honey authentication: Electrochemical genosensors for the detection o...
Morais, Stephanie; Castanheira, Michelle; Santos, Marlene; Domingues, Valentina; Delerue-Matos, Cristina; Barroso, M. Fátima; Santos, MarleneMonofloral honeys, like heather honey, are a highly sought-after ingredient. However, food safety concerns have emerged due to the number of adulterated honeys found in the global market [1,2]. Thus, this work aimed to develop an electrochemical genosensor capable of detecting the residual DNA of Erica arborea (heather flower) in commercial honey samples. Analyzing public databases, a 98-mer E. arborea DNA-targ...
Design of innovative electrochemical genosensors for honey fraud and quality de...
Morais, Stephanie L.; Castanheira, Michelle; Pereira, Eduarda; Santos, Marlene; Domingues, Valentina F.; Delerue-Matos, Cristina; Barroso, M. FátimaEnsuring food safety has become a concern for companies, consumers and the government alike, due to the increase of fraudulent and/or adulterated food products found in the global market [1,2]. Some common fraudulent strategies include mislabelling a product's geographical origin and blending it with lower-grade substances [3]. Among the frequently adulterated food products there is honey. Honey is a highly sou...
Ensuring food safety: electrochemical genosensors for the authentication of pla...
Morais, Stephanie L.; Pereira, Eduarda; Castanheira, Michelle; Santos, Marlene; Domingues, Valentina; Delerue-Matos, Cristina; Barroso, M. FátimaHoney is a high-quality and natural ingredient often consumed because of its unique sweet taste and multiple therapeutic and nutritional benefits. These properties are normally intrinsically connected to the regional flora from which the plant pollen is harvested. Hence, the botanical and geographical origins of honeys play a substantial role in the end product's composition. With the recent interest in natural...
Plant honey origin authentication: Use of electrochemical genosensors for food ...
Morais, Stephanie; Pereira, Eduarda; Castanheira, Michelle; Santos, Marlene; Domingues, Valentina; Delerue-Matos, Cristina; Barroso, M. FátimaHoney is a natural high-quality food product consumed worldwide due to its diverse nutritional profile and beneficial medical properties. These factors, along with honey’s unique sweet taste and odour, make it one of the most popular products for a healthy diet. Nevertheless, food fraud is an increasing problem with various impacts on the economy, health, and in the environment, as honey prices are established ...
Challenging invasive fungal infections: development of innovative electrochemic...
Castanheira, Michelle; Morais, Stephanie L.; Seguro, Isabel; Santos, Marlene; Lima, Luís; Pacheco, João; Barroso, M. FátimaDespite the considerable advances in the prevention and treatment of fungal infections, invasive fungus such as Candida spp., continues to be one of the major causes of morbidity and mortality. The Global Action Fund Infections reported that, annually, more than 300 million people are infected with fungal infection, from these, about 1.5 million ends up dying. Candida albicans is the most important fungal 66 op...
Electrochemical genosensors as a new approach on plant DNA detection and quanti...
Morais, Stephanie; Castanheira, Michelle; Santos, Marlene; Domingues, Valentina; Delerue-Matos, Cristina; Barroso, M. FátimaHoney is a natural sweet food product with multiple nutritional and medicinal properties making it a healthy alternative to processed sugars. With the consumers’ recent interest and pur-chase of dietary products the global honey market has greatly increased. To keep up with produc-tion, or simply for financial gain, some producers/companies are now blending pure honey with cheaper substances that possess simila...
Exploring the potential of invasive species Sargassum muticum: microwave-assist...
Silva, Aurora; Cassani, Lucia; Carpena, Maria; Lourenço-Lopes, Catarina; Grosso, Clara; Chamorro, Franklin; García-Pérez, Pascual; Carvalho, AnaSargassum muticum (SM) poses a serious environmental issue since it is a fast-expanding invasive species occupying key areas of the European shoreline, disrupting the autochthonous algae species, and disturbing the ecosystem. This problem has concerned the general population and the scientific community. Nevertheless, as macroalgae are recognized as a source of bioactive molecules, the abundance of SM presents ...
Enhancing the detection of Dinophysis spp. using electrochemical genosensors
Pereira, Eduarda; Silva, Aurora; Morais, Stephanie L.; Costa-Rama, Estefanía; Moreira, Patrícia R.; Fraga-Corral, M.; Torrado, Ana M.Background: Harmful algal blooms (HABs) pose a significant threat to the environment and public health. These blooms are defined by an accumulation of microscopic algae in water, and they can occur in lakes, rivers, estuaries, or coastal areas. Factors like the unregulated runoff of agricultural and industrial wastes into the aquatic environment [1] are believed to have transformed these ecosystems into favorab...
Design and Optimization of an Electrochemical Genosensing Platform for BDNF Val...
Caldevilla, Renato; Santos, Marlene; Barroso, M. FátimaBackground: Major depressive disorder (MDD) is a debilitating and highly prevalent psychiatric illness. Antidepressant drugs (AD) have remained the main pharmacological treatment for this condition, and since their discovery and despite their high efficacy, insufficient remission rates and treatment-resistant depression remain a cause of concern for clinicians. The BDNF gene is an extensively studied gene rega...