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The accuracy of the Montenegro skin test for leishmaniasis in PCR-negative pati...

Pinheiro,Ana Bárbara Sapienza; Kurizky,Patricia Shu; Ferreira,Marina de Freitas; Mota,Marco Antonio de Souza; Ribeiro,Jaqueline Santos

Abstract INTRODUCTION: As highly specific molecular biology-based techniques may not be sensitive enough for the diagnosis of American tegumentary leishmaniasis (ATL), clinicians frequently rely on immunological tests before treatment initiation. Hence, the correct combination of diagnostic tests is imperative for ATL diagnosis. We aimed to evaluate the accuracy of the Montenegro (Leishmanin) skin test (MST) in...

Date: 2020   |   Origin: Oasisbr

A randomized, open-label clinical trial comparing the long-term effects of milt...

Sampaio,Raimunda Nonata Ribeiro; Silva,Juliana Saboia Fontenele e; Paula,Carmen Dea Ribeiro de; Porto,Cláudia; Motta,Jorgeth de Oliveira Carneiro da

Abstract INTRODUCTION: The treatment of mucosal leishmaniasis (ML) is difficult due to the toxicity and route of administration of standard drugs. Miltefosine is an oral agent used for leishmaniasis treatment; however, no data exist regarding its use for ML in Brazil. In this study, we aimed to evaluate the efficacy of miltefosine for ML treatment compared to that of pentavalent antimonial in a pilot study. MET...

Date: 2019   |   Origin: Oasisbr

Aplicações do Deep Learning para diagnóstico de doenças e identificação de inse...

Souza,Ewerton Pacheco de; Gomes,Ciro Martins; Barroso,Daniel Holanda; Miranda,Vinícius Lima de; Gurgel-Gonçalves,Rodrigo

RESUMO Deep Learning é uma técnica de aprendizado de máquina na qual o programa computacional aprende padrões diretamente a partir de imagens classificadas previamente. O presente ensaio objetivou apresentar essa técnica e algumas de suas aplicações para diagnóstico de doenças e identificação de insetos vetores para incentivar profissionais da saúde que não tenham conhecimento aprofundado em informática e que d...

Date: 2019   |   Origin: Oasisbr

Dermatofibroma simulating seborrheic keratosis dermoscopically

Barroso,Daniel Holanda; Leite,Camila Pinon Zoby; Araujo,Gabriela Diniz de Souza; Teixeira,Márcia Almeida Galvão; Alencar,Eliane Ruth Barbosa

Abstract: Dermatofibroma is a frequent benign tumor of easy clinical diagnosis in most cases, but that can mimic other dermatoses. Dermoscopy may help to define the diagnosis and its classical pattern is a central white area, similar to a scar, surrounded by a discrete pigment network. However, dermoscopic findings are not always typical. We describe here a case of dermatofibroma exhibiting ridges, furrows and ...

Date: 2016   |   Origin: Oasisbr

Post-kala-azar dermal Leishmaniasis in two different clinical contexts

Barroso,Daniel Holanda; Silva,Claúdia Elise Ferraz; Vasconcelos,Ana Carolina Depes Perdigao e; Cavalcanti,Silvana Maria de Morais

Abstract In Brazil, visceral Leishmaniasis is caused by Leishmania chagasi. The development of cutaneous lesions in visceral leishmaniasis patients has been described in two different clinical contexts. Patients with compromised immunity can develop skin lesions as a direct consequence of a current visceral disease. Equally, patients with a history of kala-azar and progressive, immune improvement occasionally d...

Date: 2015   |   Origin: Oasisbr

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