3 documents found, page 1 of 1
cDNA cloning, molecular modeling and docking calculations of L-type lectins fro...
Maranhão, Paulo A.C.; Teixeira, Claudener S.; Sousa, Bruno L.; Barroso-Neto, Ito L.; Monteiro-Júnior, José E.; Fernandes, Andreia V.; Ramos, Marcio V.The genus Swartzia is a member of the tribe Swartzieae, whose genera constitute the living descendants of one of the early branches of the papilionoid legumes. Legume lectins comprise one of the main families of structurally and evolutionarily related carbohydrate-binding proteins of plant origin. However, these proteins have been poorly investigated in Swartzia and to date, only the lectin from S. laevicarpa s...
Cloning of cDNA sequences encoding cowpea (Vigna unguiculata) vicilins: Computa...
Rocha, Antônio J.; Sousa, Bruno L.; Girão, Matheus S.; Barroso-Neto, Ito L.; Júnior, José E. Monteiro; Oliveira, José Tadeu Abreu de; Nagano, Celso S.Vicilins are 7S globulins which constitute the major seed storage proteins in leguminous species. Variant vicilins showing differential binding affinities for chitin have been implicated in the resistance and susceptibility of cowpea to the bruchid Callosobruchus maculatus. These proteins are members of the cupin superfamily, which includes a wide variety of enzymes and non-catalytic seed storage proteins. The ...
Controlled release of Nor-β-lapachone by PLGA microparticles : a strategy for i...
Costa, Marcilia P.; Feitosa, Anderson C. S.; Oliveira, Fátima C. E.; Cavalcanti, Bruno C.; Silva, Eufrânio N. da; Dias, Gleiston G.Prostate cancer is one of the most common malignant tumors in males and it has become a major worldwide public health problem. This study characterizes the encapsulation of Nor-β-lapachone (NβL) in poly(d,l-lactide-co-glycolide) (PLGA) microcapsules and evaluates the cytotoxicity of the resulting drug-loaded system against metastatic prostate cancer cells. The microcapsules presented appropriate morphological f...