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High genetic diversity of human immunodeficiency virus type 1 in Angola

Bartolo, I; Epalanga, M; Bartolomeu, J; Fonseca, M; Mendes, A; Gama, A; Taveira, N

To investigate which HIV-1 genetic forms are circulating in Angola, we have determined the gag and/or env genotypes of 48 isolates from patients living in Cabinda and Luanda provinces. The following subtypes were identified: A(1) (18 samples, 38%), C (7,


Seronegative infection and AIDS caused by an A2 subsubtype HIV-1

Cardoso, AR; Goncalves, C; Pascoalinho, D; Gil, C; Ferreira, AF; Bartolo, I; Taveira, N

The study of true seronegative HIV-1 infections may have important implications for the diagnosis and prevention of HIV-1 infection. The case of an AIDS patient with persistently negative HIV serology is described. Genetic and phylogenetic analysis indica


Evaluation of the clinical sensitivities of three viral load assays with plasma...

Antunes, R; Figueiredo, S; Bartolo, I; Pinheiro, M; Rosado, L; Soares, I; Lourenco, H; Taveira, N

The viral load assays AMPLICOR HIV-1 Monitor Test 1.5, Nuclisens HIV-1 QT, and Quantiplex HIV RNA 3.0 (bDNA) were evaluated for their abilities to quantify human immunodeficiency virus type 1 (HIV-1) RNA in 64 plasma samples from 21 children infected in P


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