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Serious fungal infections in Portugal

Sabino, Raquel; Verissímo, Cristina; Brandão, João; Martins, C.; Alves, D.; Pais, C.; Denning, D. W.

There is a lack of knowledge on the epidemiology of fungal infections worldwide because there are no reporting obligations. The aim of this study was to estimate the burden of fungal disease in Portugal as part of a global fungal burden project. Most published epidemiology papers reporting fungal infection rates from Portugal were identified. Where no data existed, specific populations at risk and fungal infect...


Serious fungal infections in Portugal

Sabino, R.; Verissimo, C.; Brandao, J.; Martins, Carlos; Alves, D.; Pais, Célia; Denning, D. W.

There is a lack of knowledge on the epidemiology of fungal infections worldwide because there are no reporting obligations. The aim of this study was to estimate the burden of fungal disease in Portugal as part of a global fungal burden project. Most published epidemiology papers reporting fungal infection rates from Portugal were identified. Where no data existed, specific populations at risk and fungal infect...


Polymorphisms in toll-like receptor genes and susceptibility to pulmonary asper...

Carvalho, Agostinho; Pasqualotto, A. C.; Pitzurra, L.; Romani, L; Denning, D. W.; Rodrigues, Fernando José dos Santos

Toll-like receptors (TLRs) are important components of innate immunity. We investigated the association between polymorphisms in the TLR2, TLR4, and TLR9 genes and susceptibility to noninvasive forms of pulmonary aspergillosis. A significant association was observed between allele G on Asp299Gly (TLR4) and chronic cavitary pulmonary aspergillosis (odds ratio [OR], 3.46; P =.003). Susceptibility to allergic bron...


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