2 documents found, page 1 of 1
Relevance of Caspase-1 and Nlrp3 Inflammasome on Inflammatory Bone Resorption i...
Rocha, Fernanda R G. [UNESP]; Delitto, Andrea E.; de Souza, Joao A. Chaves; González-Maldonado, Laura A. [UNESP]; Wallet, Shannon M.Made available in DSpace on 2020-12-12T02:05:00Z (GMT). No. of bitstreams: 0 Previous issue date: 2020-12-01; Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP); Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES); This study investigates the role of NLRP3 inflammasome and its main effector Caspase-1 in inflammation and alveolar bone resorption associated with periodontitis. Heat-kill...
NLRC4 inflammasome has a protective role on inflammatory bone resorption in a m...
Rocha, Fernanda R.G. [UNESP]; Delitto, Andrea E.; de Souza, Joao A Chaves; Maldonado, Laura A.G. [UNESP]; Wallet, Shannon M.; Rossa, Carlos [UNESP]Made available in DSpace on 2020-12-12T01:50:04Z (GMT). No. of bitstreams: 0 Previous issue date: 2020-01-01; There is virtually no information on the role of NLRC4 inflammasome on bone resorption and inflammation associated with periodontitis. Bacterial-associated experimental periodontitis was induced in wild-type (WT) and Nlrc4-KO C57BL/6 mice. 3 μL of a 1 × 109 UFC/mL PBS suspension of heat-killed Gram-nega...