2 documents found, page 1 of 1
Weighted single-step GWAS and gene network analysis reveal new candidate genes ...
Marques, Daniele B. D.; Bastiaansen, John W. M.; Broekhuijse, Marleen L. W. J.; Lopes, Marcos S.; Knol, Egbert F.; Harlizius, BarbaraIn recent years, there has been increased interest in the study of the molecular processes that affect semen traits. In this study, our aim was to identify quantitative trait loci (QTL) regions associated with four semen traits (motility, progressive motility, number of sperm cells per ejaculate and total morphological defects) in two commercial pig lines (L1: Large White type and L2: Landrace type). Since the ...
Revealing new candidate genes for reproductive traits in pigs: combining Bayesi...
Verardo, Lucas L.; Silva, Fabyano F.; Lopes, Marcos S.; Madsen, Ole; Bastiaansen, John W. M.; Knol, Egbert F.; Kelly, Mathew; Varona, LuisReproductive traits such as number of stillborn piglets (SB) and number of teats (NT) have been evaluated in many genome-wide association studies (GWAS). Most of these GWAS were performed under the assumption that these traits were normally distributed. However, both SB and NT are discrete (e.g. count) variables. Therefore, it is necessary to test for better fit of other appropriate statistical models based on ...