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Ketamine combined with psychotherapy for treatment-resistant depression

Cohen, Rebeca; Bastos, João; Cunha, Catarina; Marguilho, Miriam; Sancho, Ana; Silva, Maria João Matos; King, Franklin; Castro-Rodrigues, Pedro

Ketamine, an N -methyl- d -aspartate antagonist, shows promise for treatment-resistant depression (TRD), with psychedelic doses potentially enhancing efficacy. However, its transient antidepressant effects and the need for repeated infusions raise concerns about optimal duration and long-term safety. Two clinical trials have tested the combination of ketamine with psychotherapy for depression, with mixed result...


Development of a Variant Process-Planning Tool: A Case Study

Santos, António Duarte; Ávila, Paulo; Santos, Bebiana; Mota, Alzira; Castro, Hélio; Ferreira, Luís Pinto; Bastos, João; Sá, José Carlos

Purpose: This study addresses the development of a variant process planning tool, following the Knowledge-Based Variant Process Planning methodology, applied in a case study and presents the gains achieved. Methodology/Approach: Case study supported by six steps: (1) Feature Analysis, (2) Knowledge Retrieval, (3) Inference, (4) Plan Adaptation, (5) Knowledge Update, and (6) Plan Validation/Optimisation. Finding...


Crew Rostering Policies and Flight Crew Safety Behaviors

Bastos, João

Este estudo investiga de que forma diferentes políticas de pedidos de atividades (i.e., bidding) nos planeamentos dos tripulantes de aviação influenciam os comportamentos de seguranças destes. Com base numa abordagem baseada em recursos, conceptualizamos as políticas de pedidos como vias de acesso a recursos, o que por consequência conferem às tripulações diferentes níveis de acesso a recursos psicológicos, enq...


Burnout Among Portuguese Residents: A Case for Change

Martins, Sebastião; Bastos, João; Mendonça, Carlos; Franco-Pego, Francisco; Durão, José; Inácio, Rafael

N/a.; N/a.

Date: 2024   |   Origin: Acta Médica Portuguesa

Comparative analysis of Multicriteria Decision‐Making methods for bus washing p...

Ávila, Paulo; Mota, Alzira; Oliveira, Eliana; Castro, Hélio; Ferreira, Luís Pinto; Bastos, João; Fernandes, Nuno O.; Moreira, Joaquim

Water is at the core of sustainable development, and its use for human activities, including vehicle washing, should be done in a sustainable way. There are several technical solutions for washing buses offering different performances, making it difficult to choose the one that best meets the requirements of each specific case. The literature on the topic hardly analyzes the choice of the best technical solutio...


Collaborative planning in non-hierarchical networks - an intelligent negotiatio...

Bastos, João; Azevedo, Américo; Ávila, Paulo; Mota, Alzira; Costa, Lino; Castro, Hélio

In today’s competing business market, companies are constantly challenged to dynamically adapt to customer expectations by diminishing the time response that goes from the beginning of the business opportunity to the satisfaction of the customer need. Simultaneously, there is increased recognition of the advantages that companies obtain in focusing on their core business and seeking other competencies through p...


NETEDGE MEP: a CNF-based multi-access edge computing platform

Ferreira, Vinicius Corrêa; Bastos, João; Martins, André; Araújo, Paulo Jorge Nicolau; Lori, Nicolas Francisco; Faria, João; Costa, António

Multi-access Edge Computing (MEC) is an active topic of research and standardization, with both the industry and academia actively planning to develop proofs-of-concept (PoCs). Implementing a standards-based MEC infrastructure is expensive and time-consuming, leading to the use of partial implementations or simulation. This paper proposes NETEDGE MEP, an open-source MEC Platform (MEP) based on cloud-native tech...


Data science for Industry 4.0 and sustainability: a survey and analysis based o...

Castro, Hélio; Costa, Filipe; Ferreira, Tânia; Ávila, Paulo; Cruz-Cunha, Manuela; Ferreira, Luís; Putnik, Goran D.; Bastos, João

In the last few years, the industrial, scientific, and technological fields have been subject to a revolutionary process of digitalization and automation called Industry 4.0. Its implementation has been successful mainly in the economic field of sustainability, while the environmental field has been gaining more attention from researchers recently. However, the social scope of Industry 4.0 is still somewhat neg...


Literature review of decision models for the sustainable implementation of Robo...

Patrício, Leonel; Ávila, Paulo; Varela, Leonilde; Cruz-Cunha, Maria Manuela; Pinto Ferreira, Luís; Bastos, João; Castro, Helio; Silva, José

Robotic Process Automation (RPA) is a rules-based system for automating business processes by software bots that mimic human interactions to relieve employees from tedious work. It was verified in the literature that there are few works related to RPA decision support models. This technology is in great growth and, therefore, it becomes important to study the evaluation of the implementation of RPA. The objecti...


Collaborative Planning in Non-Hierarchical Networks—An Intelligent Negotiation-...

Bastos, João; Azevedo, Américo; Ávila, Paulo; Mota, Alzira; Costa, Lino; Castro, Helio

In today’s competing business market, companies are constantly challenged to dynamically adapt to customer expectations by diminishing the time response that goes from the beginning of the business opportunity to the satisfaction of the customer need. Simultaneously, there is increased recognition of the advantages that companies obtain in focusing on their core business and seeking other competencies through p...


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