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Gold nanoparticle probes for colorimetric detection of plasma galectin-3: a sim...

António, Maria; Lima, Tânia; Ferreira, Rita; Fardilha, Margarida; Bastos, José Mesquita; Vitorino, Rui; Daniel-da-Silva, Ana L.

Galectin-3 (Gal-3) is a carbohydrate-binding protein associated with the development and progress of heart failure. Here, we report the first colorimetric and low-cost approach for detecting and quantifying Gal-3 using gold nanoparticles (AuNPs) bioconjugated with Gal-3 antibody. The interaction of Gal-3 with the resulting nanoprobes led to a linear response of the absorbance ratio A750nm/A526nm to Gal-3 concen...


Charlson Comorbidity Index Score and the odds of death in COVID-19 patients

Rodrigues, Leonor Carvalho; Maio, António; Freitas, Filomena; Bastos, José Mesquita; Ramalheira, Elmano


Processing and Extraction of Arterial Pulse Waves - comparison between manual a...

Martins, Maria João; Brito, Francisco da Costa; Rebelo, Pedro; Bastos, José Mesquita; Georgieva, Pétia; Leitão, Cátia



Immediate effects of a rhino-pharyngeal clearance protocol in nasal obstruction...

Alexandrino, Ana Silva; Santos, Rita; Melo, Cristina; Tomé, David; Bastos, José Mesquita; Postiaux, Guy

Introduction and objectives Children up to 2 years old are at high risk of respiratory infections and nasal irrigation is often prescribed. Yet, to date there is no sufficient knowledge about its immediate effects on the nasopharynx and middle ear. Therefore, this study aimed to analyze the effect of a rhino-pharyngeal clearance intervention protocol on nasal obstruction and middle ear condition in children und...


The OXIMAPA Study: Hypertension Control by ABPM and Association with Sleep Apne...

Maricoto, Tiago; Silva, Eurico Alves Rrodrigues; Damião, Pedro; Bastos, José Mesquita

Introduction: Ambulatory blood pressure monitoring by automatic device is the best blood pressure evaluation method and sleep apnea syndrome is the leading cause of poor control. Oximetry allows screening these individuals but its usefulness has been poorly explored in Primary Health Care. The aim was to evaluate the blood pressure control at the office and with ambulatory blood pressure monitoring by automatic...

Date: 2017   |   Origin: Acta Médica Portuguesa

Effects of a phase IV home-based cardiac rehabilitation program on cardiorespir...

Noites, Andreia; Freitas, Carla Patrícia; Pinto, Joana; Melo, Cristina; Vieira, Ágata; Albuquerque, Aníbal; Teixeira, Madalena; Ribeiro, Fernando

Cardiovascular diseases are the leading cause of death globally and sedentary lifestyle is one of the main risk factors. Home-based cardiac rehabilitation (CR) programs appear to be effective to improve exercise tolerance. The aim of the study, therefore, was to evaluate the effects of a phase IV (maintenance) home-based CR program on cardiorespiratory fitness and daily physical activity of patients recovering ...


Effects of the mediterranean diet and exercise in subjects with coronary artery...

Noites, Andreia; Pinto, Joana; Freitas, Carla Patrícia; Melo, Cristina; Albuquerque, Aníbal; Teixeira, Madalena; Bastos, José Mesquita

The association of the Mediterranean diet and exercise appears to have a protective role, reducing cardiovascular risk. This study investigated the effects of education sessions on the Mediterranean diet and an exercise program in modifying eating behaviors, body composition and abdominal fat. An experimental study was performed on 20 subjects with known coronary heart disease randomly assigned to experimental ...


Effects of microcurrents and physical exercise on the abdominal fat in patients...

Noites, Andreia; Pinto, Joana; Freitas, Carla Patrícia; Melo, Cristina; Albuquerque, Aníbal; Teixeira, Manuela; Ribeiro, Fernando; Bastos, José Mesquita

Coronary artery disease is associated with decreased levels of physical activity, contributing to increases in abdominal fat and consequently increasing metabolic risk. The innovative use of microcurrents may be an effective method to increase the lipolytic rate of abdominal adipocytes. This study aimed to investigate the effects of utilizing microcurrents in a home-based exercise program in subjects with coron...


Effects of aerobic exercise associated with abdominal microcurrent: a prelimina...

Noites, Andreia; Nunes, Rita; Gouveia, Ana Isabel; Mota, Alexandra; Melo, Cristina; Vieira, Ágata; Adubeiro, Nuno; Bastos, José Mesquita

To analyze the short- and long-term effects of microcurrent used with aerobic exercise on abdominal fat (visceral and subcutaneous). Methods: Forty-two female students from a university population were randomly assigned into five group: intervention group (IG) 1 (n=9), IG2 (n=9), IG3 (n=7), IG4 (n=8), and placebo group (PG) (n=9). An intervention program of 10 sessions encompassing microcurrent and aerobic exer...


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