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Anti-phospholipase A2 receptor antibodies: Current applications in primary memb...

Background: Membranous nephropathy (MN) is among the most common causes of nephrotic syndrome in nondiabetic adults. The podocytic M-type phospholipase A2 receptor (PLA2R) has been identified as the major antigenic target of the immune response that underlies primary membranous nephropathy (PMN). In the last decade, anti-PLA2R antibodies have been seen as promising diagnostic biomarkers for PMN. Other potential...