2 documents found, page 1 of 1
Evaluation of partial thromboplastin time, thrombin time and prothrombin time o...
Miranda, Vanessa Maria Andrade Machado; Barbosa Filho, José Pedro Martins; Costa, Romero Marcos Pedrosa Brandão; Leite, Ana Cristina LimaFibrinolytic proteases are enzymes that degrade the fibrin, a main component of the blood clot. Thus, the present study aimed to understand the evaluation of aPTT, TT and PT on plasma treated with a fibrinolytic protease produced by Mucor subtillissimus. To assess the anticoagulant effect, the protease was used in different concentrations of 0.5-2.5mg/mL. The tests showed that the enzyme promoted a significant ...
Protease with fibrinolytic and collagenolytic activity produced by Aspergillus ...
Cardoso, Kethylen Barbara Barbosa; Nascimento, Thiago Pajeú; Oliveira, Vagne de Melo; Costa, Romero Marcos Pedrosa Brandão; Pastrana, LorenzoProteases play a fundamental role in the economy, being present in several industrial sectors. Among the fungi known to produce proteases, the genus Aspergillus stands out. Thus, the objective of this work was to produce proteases from solid state fermentation of Aspergillus ochraceus, purify, characterize and evaluate their potential in the production of collagenolytic and fibrinolytic enzymes. For this, the t...