5 documents found, page 1 of 1
Preparation, characterization and evaluation of guar films impregnated with rel...
Batista, P; Castro, PM; Madureira, AR; Sarmento, B; Pintado, MBackground: Biological molecules such as therapeutic proteins and peptides have provided ample opportunities for further improvements in health and wellbeing. However, such biomacro-molecules face stability challenges regarding premature processing and digestion, whenever any enteric delivery route is considered. Hence, oral guar films entrapping peptide-containing chitosan microparticles have been developed as...
Morphological Changes of the Internal Carotid Artery: Prevalence and Characteri...
Martins, H; Mayer, A; Batista, P; Soares, F; Almeida, V; Pedro, AJ; Oliveira, VBackground and purpose: Morphological changes of the internal carotid arteries (McICA) are frequently found during cervical ultrasound studies. However, the etiology of McICA remains controversial. During this study, the prevalence and demographic characteristics of McICA, such as kinking, coiling or looping identified by Doppler ultrasound, were analysed and its relationship with vascular risk factors and stro...
The Stress Response to Surgery and Postoperative Delirium: Evidence of Hypothal...
Cerejeira, J; Batista, P; Nogueira, V; Vaz-Serra, A; Mukaetova-Ladinska, EBIntroduction: The aim of this study is to determine whether postoperative delirium is associated with dysregulation of hypothalamic—pituitary—adrenal and growth hormone/insulin-like growth factor 1 (GH/IGF-1) responses following acute systemic inflammation. Methods: Plasma levels of cortisol, IGF-1, C-reactive protein, interleukin (IL)-6, IL-8, and IL-10 were measured before and after surgery in 101 patients 60...
Low preoperative plasma cholinesterase activity as a risk marker of postoperati...
Cerejeira, J; Batista, P; Nogueira, V; Vaz-Serra, A; Mukaetova-Ladinska, EBBACKGROUND: delirium is a frequent neuropsychiatric syndrome affecting medical and surgical elderly patients. Cholinergic dysfunction has been implicated in delirium pathophysiology and plasmatic acetylcholinesterase (AChE) and butyrylcholinesterase (BuChE) activities are suppressed in patients with delirium. In this cohort study, we investigated whether these changes emerge during delirium or whether they are ...
Familial infection by the hepatitis C virus.
Miranda, H P; Batista, P; Oliveira, F; Barros, HThe aim of this study was to evaluate the prevalence of the antibody to hepatitis C virus (HCV) in the relatives of cases of asymptomatic chronic hepatitis C infection, detected during routine blood donation, and determine risk factors for the presence of the infection in the family setting. Two hundred and eighty-five relatives (spouses, offspring, siblings and parents) of 87 index cases were studied. Anti-HCV...