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A Preliminary Investigation of Salmonella Populations in Indigenous Portuguese ...

Miranda, C; Batista, S; Mateus, TL; Vieira-Pinto, M; Ribeiro, V; Dantas, R; Brito, NV

The sustainability of agroecological systems, biodiversity protection, animal welfare, and consumer demand for higher quality products from alternative and extensive farming methods have reinforced interest in local breeds that are well adapted to low-input environments. However, food safety needs to be safeguarded to reinforce consumer confidence. The aim of this study was to conduct a preliminary investigatio...


REALMS Study: Real-World Effectiveness and Safety of Fingolimod in Patients wit...

Batista, S; Nunes, CC; Cerqueira, JJ; Martins Silva, A; Correia de Sá, J; Ferreira, J; Mendonça, MT; Pinheiro, J; Salgado, V; Correia, AS; Sequeira, J

Background: Fingolimod, an oral sphingosine 1-phosphate receptor modulator, is approved by EMA for relapsing-remitting multiple sclerosis (RRMS). Objectives: To assess the effectiveness and safety of fingolimod in patients with RRMS in real-world clinical practice in Portugal. Methods: Retrospective, multicentre, non-interventional study, reporting 3 years follow-up of data collected from October 2015 to July 2...


REALMS study: real-world effectiveness and safety of fingolimod in patients wit...

Batista, S; Nunes, C; Cerqueira, J; Silva, A; Sá, J; Ferreira, J; Mendonça, M; Pinheiro, J; Salgado, V, et al.

Background: Fingolimod, an oral sphingosine 1-phosphate receptor modulator, is approved by EMA for relapsing-remitting multiple sclerosis (RRMS). Objectives: To assess the effectiveness and safety of fingolimod in patients with RRMS in real-world clinical practice in Portugal. Methods: Retrospective, multicentre, non-interventional study, reporting 3 years follow-up of data collected from October 2015 to July 2...


Giant Paratubal Cyst Presenting As Adnexal Torsion: a Case Report

Alpendre, F; Pedrosa, I; Silva, R; Batista, S; Tapadinhas, P

Background: Paraovarian/paratubal cysts constitute about 10% of adnexal masses and are usually small and asymptomatic. A huge paratubal cyst complicated by adnexal torsion is a rare cause of acute low abdominal pain. Case report: We report the case of an obese 31-year-old nulliparous woman who presented with a large pelvic cyst causing ovarian torsion. The size of the mass (~25 cm) caused pain, and obesity led ...


Consensus Recommendations of the Multiple Sclerosis Study Group and Portuguese ...

Abreu, P; Pedrosa, R; Sá, MJ; Cerqueira, J; Sousa, L; Da Silva, AM; Pinheiro, J; De Sá, J; Batista, S; Simões, RM; Pereira, DJ; Vilela, P; Vale, J

INTRODUCTION: Magnetic resonance imaging is established as a recognizable tool in the diagnosis and monitoring of multiple sclerosis patients. In the present, among multiple sclerosis centers, there are different magnetic resonance imaging sequences and protocols used to study multiple sclerosis that may hamper the optimal use of magnetic resonance imaging in multiple sclerosis. In this context, the Group of St...


Consensus Recommendations of the Multiple Sclerosis Study Group and Portuguese ...

Abreu, P; Pedrosa, R; Sá, MJ; Cerqueira, J; Sousa, L; Da Silva, AM; Pinheiro, J; De Sá, J; Batista, S; Simões, RM; Pereira, DJ; Vilela, P; Vale, J

INTRODUCTION: Magnetic resonance imaging is established as a recognizable tool in the diagnosis and monitoring of multiple sclerosis patients. In the present, among multiple sclerosis centers, there are different magnetic resonance imaging sequences and protocols used to study multiple sclerosis that may hamper the optimal use of magnetic resonance imaging in multiple sclerosis. In this context, the Group of St...


The neural basis of fatigue in multiple sclerosis: A multimodal MRI approach

Novo, AM; Batista, S; Alves, C; d'Almeida, OC; Marques, IB; Macário, C; Santana, I; Sousa, L; Castelo-Branco, M; Cunha, L

BACKGROUND: Fatigue is a frequent disabling symptom in multiple sclerosis (MS), but its pathophysiology remains incompletely understood. This study aimed to explore the underlying neural basis of fatigue in patients with MS. METHODS: We enrolled 60 consecutive patients with MS and 60 healthy controls (HC) matched on age, sex, and education. Fatigue was assessed using the Portuguese version of the Modified Fatig...


Plasma exchange in severe acute relapses of multiple sclerosis - Results from a...

Correia, I; Ribeiro, JJ; Isidoro, L; Batista, S; Nunes, C; Macário, C; Borges, C; Tomaz, J; Sousa, L

Relapses in Multiple Sclerosis (MS) are often associated with significant disability impairment which is resultant from poor response to corticosteroids. In such severe cases, plasma exchange (PLEX) may be used, although only a few studies with MS patients have been reported. Our objective was to evaluate the effectiveness of PLEX in severe relapses of MS. METHODS: Retrospective study of MS patients treated wit...


Consensus Recommendations of the Multiple Sclerosis Study Group and Portuguese ...

Abreu, P; Pedrosa, R; Sá, MJ; Cerqueira, J; Sousa, L; Martins da Silva, A; Pinheiro, J; De Sá, J; Batista, S; Moiron Simões, R; Jardim Pereira, D

INTRODUCTION: Magnetic resonance imaging is established as a recognizable tool in the diagnosis and monitoring of multiple sclerosis patients. In the present, among multiple sclerosis centers, there are different magnetic resonance imaging sequences and protocols used to study multiple sclerosis that may hamper the optimal use of magnetic resonance imaging in multiple sclerosis. In this context, the Group of St...


Cognitive impairment and magnetic resonance imaging correlates in primary progr...

Gouveia, A; Dias, SP; Santos, T; Rocha, H; Coelho, CR; Ruano, L; Galego, O; Diogo, MC; Seixas, D; Sá, MJ; Batista, S

Objectives: To characterize cognitive impairment in primary progressive multiple sclerosis (PPMS) and to correlate the pattern of cognitive deficits with brain magnetic resonance imaging (MRI) volumetric data. Materials and methods: In a multicenter cross-sectional study, we recruited consecutive patients with PPMS as well as age, sex, and education level-matched healthy controls (HC). All participants underwen...


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