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IgG+ Extracellular Vesicles Measure Therapeutic Response in Advanced Pancreatic...

Couto, Nuno; Elzanowska, Julia; Maia, Joana; Batista, Silvia; Pereira, Catarina Esteves; Beck, Hans Christian; Carvalho, Ana Sofia

(1) Background: Pancreatic ductal adenocarcinoma (PDAC) is expected to be the second-leading cause of cancer deaths by 2030. Imaging techniques are the standard for monitoring the therapy response in PDAC, but these techniques have considerable limits, including delayed disease progression detection and difficulty in distinguishing benign from malignant lesions. Extracellular vesicle (EV) liquid biopsy is an em...


The influence of planning and response inhibition on cognitive functioning of N...

Moniz, Marco; Jesus, Saul Neves de; Pacheco, Andreia; Gonçalves, Eduardo; Viseu, J.; Brás, Marta; Silva, Dina; Batista, Silvia

Depression is one of the main risk factors for suicide. However, little is known about the intricate relationships among depressive symptomatology in unipolar depression, suicide risk, and the characteristics of executive dysfunction in depressed patients. We compared 20 non-psychotic unipolar depressed suicide attempters to 20 matching depressed non-attempters and to 20 healthy controls to further investigate ...


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