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Analysis of shared heritability in common disorders of the brain

Anttila, Verneri; Bulik-Sullivan, Brendan; Finucane, Hilary K.; Walters, Raymond K.; Bras, Jose; Duncan, Laramie; Escott-Price, Valentina

Disorders of the brain can exhibit considerable epidemiological comorbidity and often share symptoms, provoking debate about their etiologic overlap. We quantified the genetic sharing of 25 brain disorders from genome-wide association studies of 265,218 patients and 784,643 control participants and assessed their relationship to 17 phenotypes from 1,191,588 individuals. Psychiatric disorders share common varian...


World Federation of Societies of Biological Psychiatry (WFSBP) Guidelines for b...

Bauer, Michael; Whybrow, Peter C.; Angst, Jules; Versiani, Marcio; Möller, Hans-Jürgen

These practice guidelines for the biological treatment of unipolar depressive disorders were developed by an international Task Force of the World Federation of Societies of Biological Psychiatry (WFSBP). The goal for developing these guidelines was to systematically review all available evidence pertaining to the treatment of unipolar depressive disorders, and to produce a series of practice recommendations th...

Date: 2009   |   Origin: Oasisbr

World Federation of Societies of Biological Psychiatry (WFSBP) Guidelines for b...

Bauer, Michael; Whybrow, Peter C.; Angst, Jules; Versiani, Marcio; Möller, Hans-Jürgen

These practice guidelines for the biological treatment of unipolar depressive disorders were developed by an international Task Force of the World Federation of Societies of Biological Psychiatry (WFSBP). The goal for developing these guidelines was to systematically review all available evidence pertaining to the treatment of the complete spectrum of unipolar depressive disorders, and to produce a series of pr...

Date: 2009   |   Origin: Oasisbr

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