5 documents found, page 1 of 1
Fostering conservancy through bioprospection: the pharmaceutical value of the b...
Sahm, Bianca Del Bianco; Guimarães, Larissa Alves; Wilke, Diego Veras; Bauermeister, Anelize; Costa-Lotufo, Leticia Veras; Jimenez, Paula C.The inherent value of nature is immeasurable. That being said, through bioprospection – the systematic search for functional products or processes from living organisms –, the oceans and marine life have emerged as a relevant source of biodiscoveries that hold significant economic worth. Particularly considering the pharmaceutical industry, an increasing number of natural molecules of marine origin have been ma...
Ion identity molecular networking for mass spectrometry-based metabolomics in t...
Schmid, Robin; Petras, Daniel; Nothias, Louis-Félix; Wang, Mingxun; Aron, Allegra T.; Jagels, Annika; Tsugawa, Hiroshi; Rainer, JohannesMade available in DSpace on 2022-04-28T19:40:47Z (GMT). No. of bitstreams: 0 Previous issue date: 2021-12-01; National Institute of General Medical Sciences; Molecular networking connects mass spectra of molecules based on the similarity of their fragmentation patterns. However, during ionization, molecules commonly form multiple ion species with different fragmentation behavior. As a result, the fragmentation ...
In vitro metabolism of copalic and kaurenoic acids in rat and human liver micro...
Mauro, Mariana [UNESP]; da Silva, Rodrigo Moreira; de Campos, Michel Leandro; Bauermeister, Anelize; Lopes, Norberto PeporineMade available in DSpace on 2022-04-29T08:32:13Z (GMT). No. of bitstreams: 0 Previous issue date: 2021-01-01; Copalic (CA) and kaurenoic (KA) acids are the main diterpenes found in the oleoresin extracted from the copaiba tree (Copaifera sp). This study aimed to characterize the metabolism of CA and KA in rat and human liver microsomes using liquid chromatography with tandem mass spectrometry (LC-MS/MS). The in...
Can Statistical Evaluation Tools for Chromatographic Method Development Assist ...
Mannochio-Russo, Helena [UNESP]; Bueno, Paula Carolina P.; Bauermeister, Anelize; De Almeida, Rafael Felipe; Dorrestein, Pieter C.Made available in DSpace on 2021-06-25T10:45:11Z (GMT). No. of bitstreams: 0 Previous issue date: 2020-11-25; Proper chromatographic methods may reduce the challenges inherent in analyzing natural product extracts, especially when utilizing hyphenated detection techniques involving mass spectrometry. As there are many variations one can introduce during chromatographic method development, this can become a daun...
Phytochemical and chemotaxonomy investigation of polar crude extract from Erema...
Bauermeister, Anelize