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Proof-of-Concept Study of Multifunctional Hybrid Nanoparticle System Combined w...
Lopes, Joana; Ferreira-Gonçalves, Tânia; Figueiredo, Isabel V.; Rodrigues, Cecília M. P.; Ferreira, Hugo; Ferreira, David; Viana, Ana S.; Faísca, PedroThe global impact of cancer emphasizes the importance of developing innovative, effective and minimally invasive therapies. In the context of superficial cancers, the development of a multifunctional nanoparticle-based system and its in vitro and in vivo safety and efficacy characterization are, herein, proposed as a proof-of-concept. This multifunctional system consists of gold nanoparticles coated with hyalur...
Proof-of-Concept Study of Multifunctional Hybrid Nanoparticle System Combined w...
Lopes, Joana; Ferreira-Gonçalves, Tânia; Figueiredo, Isabel V.; Rodrigues, Cecília M. P.; Ferreira, Hugo; Ferreira, David; Viana, Ana S.; Faísca, PedroThe global impact of cancer emphasizes the importance of developing innovative, effective and minimally invasive therapies. In the context of superficial cancers, the development of a multifunctional nanoparticle-based system and its in vitro and in vivo safety and efficacy characterization are, herein, proposed as a proof-of-concept. This multifunctional system consists of gold nanoparticles coated with hyalur...
Proof-of-Concept Study of Multifunctional Hybrid Nanoparticle System Combined w...
Lopes, Joana; Ferreira-Gonçalves, Tânia; Figueiredo, Isabel V.; Rodrigues, Cecília M. P.; Ferreira, Hugo; Ferreira, David; Viana, Ana S.; Faísca, PedroThe global impact of cancer emphasizes the importance of developing innovative, effective and minimally invasive therapies. In the context of superficial cancers, the development of a multifunctional nanoparticle-based system and its in vitro and in vivo safety and efficacy characterization are, herein, proposed as a proof-of-concept. This multifunctional system consists of gold nanoparticles coated with hyalur...
Current Trends in Cancer Nanotheranostics: Metallic, Polymeric, and Lipid-Based...
Silva, Catarina Oliveira; Pinho, Jacinta Oliveira; Lopes, Joana Margarida; Almeida, António José; Gaspar, Maria Manuela; Reis, Catarina PintoTheranostics has emerged in recent years to provide an efficient and safer alternative in cancer management. This review presents an updated description of nanotheranostic formulations under development for skin cancer (including melanoma), head and neck, thyroid, breast, gynecologic, prostate, and colon cancers, brain-related cancer, and hepatocellular carcinoma. With this focus, we appraised the clinical adva...
EGF functionalized polymer-coated gold nanoparticles promote EGF photostability...
Silva, Catarina Oliveira; Petersen, Steffen B.; Reis, Catarina Pinto; Rijo, Patricia; Molpeceres, Jesus; Fernandes, Ana SofiaThe application of functionalized nanocarriers on photothermal therapy for cancer ablation has wide interest. The success of this application depends on the therapeutic efficiency and biocompatibility of the system, but also on the stability and biorecognition of the conjugated protein. This study aims at investigating the hypothesis that EGF functionalized polymer -coated gold nanoparticles promote EGF photost...
Nanopartículas de PCL com acetato de hidrocortisona como uma terapia dermatológ...
Reis, Catarina Pinto; Jerónimo, Ana Rita Gonçalves; Pinto, Pedro Contreiras; Silva, Catarina Oliveira; Candeias, SaraA dermatite atópica é uma patologia cutânea crónica que requer cuidados intensivos da pele e tratamento farmacológico; contudo, os tratamentos disponíveis necessitam urgentemente de ser melhorados, especialmente quando utilizados por períodos longos ou em grupos específicos (ex: crianças). A nanotecnologia tem contribuído com sistemas de veiculação inovadores e pode oferecer terapias efectivas e direcionadas. O...