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Insulin resistance as a predictor of cardiovascular diseases
Domingues, Neuza
Date: 2021
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Origin: Estudo Geral - Universidade de Coimbra
Cholesteryl hemiesters alter lysosome structure and function and induce proinfl...
Domingues, Neuza; Estronca, Luís M.B.B.; Silva, João; Encarnação, Marisa R.; Mateus, Rita; Silva, Diogo Pinto Lobo Jesus; Santarino, Inês B.Rationale: Cholesteryl hemiesters are oxidation products of polyunsaturated fatty acid esters of cholesterol. Their oxo-ester precursors have been identified as important components of the "core aldehydes" of human atheromata and in oxidized lipoproteins (Ox-LDL). We had previously shown, for the first time, that a single compound of this family, cholesteryl hemisuccinate (ChS), is sufficient to cause irreversi...
Date: 2017
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Origin: RepositóriUM - Universidade do Minho