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Cost of Immune Tolerance Induction in Hemophilia A Patients: Results from the I...

Fusco, F; Gringeri, A; Scalone, L; Mantovani, L; Rocino, A; Altisent, C; Astermark, J; Diniz, MJ; Fijnvandraat, K; Klamroth, R; Lambert, T

Date: 2011   |   Origin: Repositório do Centro Hospitalar de Lisboa Central, EPE
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Non-Genetic Risk Factors and the Development of Inhibitors in Haemophilia: a Co...

Astermark, J; Altisent, C; Batorova, A; Diniz, MJ; Gringeri, A; Holme, PA; Karafoulidou, A; Lopez-Fernández, MF; Reipert, BM; Rocino, A; Schiavoni, M

The development of inhibitors to the infused factor in patients with haemophilia is a serious clinical problem. Recent evidence suggests that alongside the strong genetic contribution to inhibitor formation, there are a number of non-genetic factors--perceived by the immune system as danger signals--which promote formation of inhibitors. This study provides a comprehensive review of clinical studies relating to...

Date: 2010   |   Origin: Repositório do Centro Hospitalar de Lisboa Central, EPE
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