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Split-hand and split-limb phenomena in amyotrophic lateral sclerosis: pathophys...

Corcia, Philippe; Bede, Peter; Pradat, Pierre-François; Couratier, Philippe; Vucic, Steve; Carvalho, Mamede

Amyotrophic lateral sclerosis (ALS) is a progressive neurodegenerative disorder affecting the upper and lower motor neurons. A key clinical feature of ALS is the absence of accurate, early-stage diagnostic indicators. 'Split-hand syndrome' was first described in ALS at the end of the last century and a considerable body of literature suggests that the split-hand phenomenon may be an important clinical feature o...

Date: 2021 | Origin: Repositório da Universidade de Lisboa

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