2 documents found, page 1 of 1
Watch and wait after neoadjuvant treatment in rectal cancer: comparison of outc...
Temmink, SJ; Peeters, KC; Bahadoer, R; Kranenbarg, MK; Roodvoets, AG; Melenhorst, J; Burger, JW; Wolthuis, A; Renehan, AG; Figueiredo, NL; Pares, OrBackground: In rectal cancer, watch and wait for patients with a cCR after neoadjuvant treatment has an established evidence base. However, there is a lack of consensus on the definition and management of a near-cCR. This study aimed to compare outcomes in patients who achieved a cCR at first reassessment versus later reassessment. Methods: This registry study included patients from the International Watch & Wa...
Tumour ADC measurements in rectal cancer: effect of ROI methods on ADC values a...
Lambregts, DM; Beets, GL; Maas, M; Curvo-Semedo, L; Kessels, AG; Thywissen, T; Beets-Tan, RGOBJECTIVES: To assess the influence of region of interest (ROI) size and positioning on tumour ADC measurements and interobserver variability in patients with locally advanced rectal cancer (LARC). METHODS: Forty-six LARC patients were retrospectively included. Patients underwent MRI including DWI (b0,500,1000) before and 6-8 weeks after chemoradiation (CRT). Two readers measured mean tumour ADCs (pre- and post...