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Risks of Maternal Obesity in Pregnancy: A Case-control Study in a Portuguese Ob...

Alves, P; Malheiro, MF; Gomes, JC; Ferraz, T; Montenegro, N

Objective The present study aims to understand to what extent obesity is related to adverse maternal, obstetrical, and neonatal outcomes in a Portuguese obstetrical population. Methods A retrospective case-control study was conducted at the Department of Obstetrics of a differentiated perinatal care facility. The study compared 1,183 obese pregnant women with 5,399 normal or underweight pregnant women for the o...


A parallel increase in placental oxidative stress and antioxidant defenses occu...

Araujo, JR; ramalho, c; Correia Branco, A; Faria, A; Ferraz, T; Keating, E; Martel, F

We aimed to determine the oxidative stress status in placentas obtained from gestational (GDM) and type 1 (T1D) diabetic pregnancies. Malonaldehyde and protein carbonyls, two biomarkers of oxidative damage, were higher in T1D but not in GDM placentas. Also, higher reduced glutathione and lower oxidized glutathione levels and higher glutathione peroxidase activity were found in T1D but not in GDM placentas. Thes...


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