3 documents found, page 1 of 1
Green spaces and respiratory, cardiometabolic, and neurodevelopmental outcomes:...
Fernandes, A; Avraam, D; Cadman, T; Dadvand, P; Guxens, M; Binter, A-C; Pinot de Moira, A; Nieuwenhuijsen, M; Duijts, L; Julvez, J; De Castro, MStudies evaluating the benefits and risks of green spaces on children's health are scarce. The present study aimed to examine the associations between exposure to green spaces during pregnancy and early childhood with respiratory, cardiometabolic, and neurodevelopmental outcomes in school-age children. We performed an Individual-Participant Data (IPD) meta-analysis involving 35,000 children from ten European bi...
Mannosylated glycans impair normal T-cell development by reprogramming commitme...
Vicente, MM; Alves, I; Fernandes, Â; Dias, AM; Santos-Pereira, B; Pérez-Anton, E; Santos, S; Yang, T; Correia, A; Münster-Kühnel, A; Almeida, ARMT-cell development ensures the formation of diverse repertoires of T-cell receptors (TCRs) that recognize a variety of antigens. Glycosylation is a major posttranslational modification present in virtually all cells, including T-lymphocytes, that regulates activity/functions. Although these structures are known to be involved in TCR-selection in DP thymocytes, it is unclear how glycans regulate other thymic dev...
Exposure to natural environments during pregnancy and birth outcomes in 11 euro...
Torres Toda, M; Avraam, D; James Cadman, T; Fossati, S; de Castro, M; Dedele, A; Donovan, G; Elhakeem, A; Estarlich, M; Fernandes, A; Gonçalves, RResearch suggests that maternal exposure to natural environments (i.e., green and blue spaces) promotes healthy fetal growth. However, the available evidence is heterogeneous across regions, with very few studies on the effects of blue spaces. This study evaluated associations between maternal exposure to natural environments and birth outcomes in 11 birth cohorts across nine European countries. This study, par...