7 documents found, page 1 of 1
Genética e hanseníase
Beiguelman,BernardoAs diferentes linhas de pesquisa utilizadas para investigar a importância dos fatores hereditários humanos na determinação da resistência/suscetibilidade à infecção pelo Mycobacterium leprae foram discutidas no presente trabalho. Uma síntese dessas abordagens permitiu analisar os resultados das investigações sobre associação da hanseníase com polimorfismos genéticos, distribuição familial da hanseníase, prevalê...
Twinning rate in a sample from a Brazilian hospital with a high standard of rep...
Colletto,Gloria Maria Duccini Dal; Segre,Conceição Aparecida de Mattos; Beiguelman,BernardoCONTEXT: Epidemiological studies on twin births have been motivated mostly by the positive correlation between twinning rate and human fertility, prematurity, low birth weight, increased risk of infant death and long term risk for morbidity. OBJECTIVE: This paper intends to estimate the incidence of multiple births in a private hospital in Brazil with a high standard of reproductive care, and to evaluate the ef...
Perinatal mortality among twins and singletons in a city in southeastern Brazil...
Beiguelman,Bernardo; Franchi-Pinto,CarlaAnalysis of 116,699 deliveries (1062 twin pairs and 115,637 singletons) which occurred from 1984 to 1996 at the largest obstetric center in Campinas, SP, Brazil, provided the following conclusions: 1) despite the low percentage of twin births (0.9%), 10.7% of all early neonatal deaths and 3.5% of all stillbirths were twins. Compared to singletons, the likelihood of stillbirths and early neonatal deaths among tw...
Genetic effect on apgar score
Franchi-Pinto,Carla; Colletto,Glória Maria Duccini Dal; Krieger,Henrique; Beiguelman,BernardoIntraclass correlation coefficients for one- and five-min Apgar scores of 604 twin pairs born at a southeastern Brazilian hospital were calculated, after adjusting these scores for gestational age and sex. The data support a genetic hypothesis only for 1-min Apgar score, probably because it is less affected by the environment than 4 min later, after the newborns have been under the care of a neonatology team. F...
Birth weight of twins: 1. The fetal growth patterns of twins and singletons
Beiguelman,Bernardo; Colletto,Gloria M.D.D.; Franchi-Pinto,Carla; Krieger,HenriqueDistributions of birth weights of twins and singletons born at three southeastern Brazilian hospitals were compared after adjustment for gestational age, its quadratic and cubic terms, sex, type of pregnancy, as well as their interactions. The pattern of twin fetal growth rate was retarded in comparison to that of singletons, regardless of the socioeconomic level of the examined population, but the gestational ...
Birth weight of twins: 2. Fetal genetic effect on birth weight
Beiguelman,Bernardo; Colletto,Glória M.D.D.; Franchi-Pinto,Carla; Krieger,HenriqueIntraclass correlation coefficients were calculated for the birth weights of twins born at three southeastern Brazilian hospitals, after adjustment of the natural logarithms of these weights for gestational age, its quadratic and cubic terms, sex, and their interactions. The data indicate that fetal genetic effect on birth weight might have the opportunity to be demonstrated by children born to undernourished w...
Maternal age and Down syndrome in Southeastern Brazil
Beiguelman,Bernardo; Krieger,Henrique; Silva,Luciana Marques daThe proportion of maternal-age-independent patients estimated among 200 Brazilian Down syndrome children (59.6%) was significantly larger than that of maternal-age-dependent cases (40.4%). The latter proportion is the smallest observed in pertinent literature and due basically to the low mean maternal age of the population analyzed. Based on the remarkable correlation (r = 0.95) between the proportion of matern...