2 documents found, page 1 of 1
Computational Insights into the Interplay of Mechanical Forces in Angiogenesis
Guerra, A; Belinha, J; Salgado, CL; Monteiro, FJ; Jorge, RNThis study employs a meshless computational model to investigate the impacts of compression and traction on angiogenesis, exploring their effects on vascular endothelial growth factor (VEGF) diffusion and subsequent capillary network formation. Three distinct initial domain geometries were defined to simulate variations in endothelial cell sprouting and VEGF release. Compression and traction were applied, and t...
The computational mechanics of bone tissue: biologic behaviour, remodelling alg...
Belinha, J; Manzanares-Céspedes, M; Completo, AntónioThis book offers a timely snapshot of computational methods applied to the study of bone tissue. The bone, a living tissue undergoing constant changes, responds to chemical and mechanical stimuli in order to maximize its mechanical performance. Merging perspectives from the biomedical and the engineering science fields, the book offers some insights into the overall behavior of this complex biological tissue. I...