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Genetic determinants for prediction of outcome of patients with papillary thyro...

Póvoa, AA; Teixeira, E; Bella-cueto, MR; Batista, R; Pestana, A; Melo, M; Alves, T; Pinto, M; Sobrinho-Simões, M; Maciel, J; Soares, P

Papillary thyroid carcinoma (PTC) usually presents an excellent prognosis, but some patients present with aggressive metastatic disease. BRAF, RAS, and TERT promoter (TERTp) genes are altered in PTC, and their impact on patient outcomes remains controversial. We aimed to determine the role of genetic alterations in PTC patient outcomes (recurrent/persistent disease, structural disease, and disease-specific mort...

Date: 2021   |   Origin: Repositório Aberto da Universidade do Porto
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