3 documents found, page 1 of 1
Thrombocytopenia: diagnosis with flow cytometry and antiplatelet antibodies
Guerra,João Carlos de Campos; Kanayama,Ruth Hissae; Nozawa,Sonia Tsukasa; Ioshida,Márcia Regina; Takiri,Irina Yoko; Lazaro,Robson JoséObjective: To identify antiplatelet antibodies by flow cytometry (direct method) in patients with thrombocytopenia. Methods: Between January 1997 and March 2004 a total of 15100 patients were referred to the Centro de Hematologia de São Paulo for hematological investigation of several diagnoses (anemia, leukopenia, thrombocytopenia, coagulation abnormalities, adenomegaly, leukemia and others). Of those, 1057 we...
Correlation between flow cytometry and histologic findings: ten year experience...
Bezerra,Alanna Mara Pinheiro Sobreira; Pasqualin,Denise da Cunha; Guerra,João Carlos de Campos; Colombini,Marjorie ParisObjective: To demonstrate the advantages of correlating flow cytometry immunophenotyping with the pathology/ immunohistochemistry of lymph nodes or nodules in the diagnosis of lymphoproliferative diseases. Methods: A retrospective study was carried out of 157 biopsy or fine-needle aspiration lymph nodes/ nodule specimens taken from 142 patients, from 1999 and 2009. The specimens were simultaneously studied with...
A importância da citometria de fluxo no diagnóstico raro de mieloma mielomonocí...
Bacal,Nydia Strachman; Guerra,João Carlos de Campos; Ferreira,Eurípedes; Nozawa,Sonia Tsukasa; Kanayama,Ruth Hissae; Di Pietro,Daniel; Borovik,CleideO mieloma múltiplo consiste na proliferação de células plasmáticas. Raramente apresenta, ao diagnóstico, morfologia de células imaturas com citoplasma amplo basofílico, sugerindo quadro leucêmico inicial. O objetivo deste artigo é mostrar a importância da imunofenotipagem na elucidação destes achados morfológicos pela expressão simultânea de antígenos plasmocíticos, mielomonocíticos e de linhagem linfóide T, co...