2 documents found, page 1 of 1
Purification of a Lectin from the Marine Red Alga Gracilaria cornea and Its Eff...
Lima, Maria E. P.; Carneiro, Maria E.; Nascimento, Antônia E.; Grangeiro, Thalles B.; Holanda, Marjory L.; Amorim, Rodrigo C. N.; Benevides, Norma M. B.A lectin was purified from the seaweed Gracilaria cornea by hydrophobic interaction chromatography on phenyl-Sepharose CL-4B followed by affinity chromatography on immobilized mucin. Sodium dodecyl sulfate-polyacrylamide gel electrophoresis of G. cornea lectin (GCL) revealed a single protein band of approximately 60 kDa, whereas by gel filtration on Sephadex G-100 its native molecular mass was 66 kDa. GCL exhib...
Peripheral antinociception and anti-edematogenic effect of a sulfated polysacch...
Quinderé, Ana L. G.; Fontes, Bruno P.; Vanderlei, Edfranck de S. O.; Rodrigues, José A. G.; Araújo, Ianna W. F. de; Jorge, Roberta J. B.Background: Sulfated polysaccharides from red marine algae have presented a variety of potentially therapeutic biological effects, however, their antinocicpetive and anti-inflammatory properties are not well understood. Methods: Male Swiss mice were pretreated with a sulfated polysaccharidic fraction obtained from the marine alga Acanthophora muscoides (AmII) (1, 3 or 9 mg/kg, iv) 30 min prior to either receivi...