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Neuroprotective effects of mitochondria-targeted antioxidants in a Parkinson’s ...

Costa , I.; Benfeito , S.; Silva , V.; Cagide , F.; Borges , F.; Remião , F.; Silva , R.

Background: Parkinson’s disease (PD) is a neurodegenerative disease with early prominent death of dopaminergic neurons in the substantia nigra pars compacta, concurrently with Lewys body formation, iron accumulation, oxidative stress and ferroptosis[1–3]. Since there is no effective therapy capable of stopping/delaying disease progression, phenolic acids such as hydroxycinnamic and hydroxybenzoic acids (HCA and...

Date: 2023   |   Origin: Scientific Letters

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