8 documents found, page 1 of 1
Enhancing primary prevention: the incremental predictive value of high-sensitiv...
Andraz, S.; Pereira, J. Massa; Costa, H.; Espirito Santo, M.; Hamann, L.; Fernandes, R.; Bispo, J.; Carvalho, D.; Bento, D.; Azevedo, P.; Mimoso, J.Atherosclerotic cardiovascular disease (ASCVD) is a global health challenge, prompting widespread use of conventional risk assessment tools (SCORE2 in Europe and the ASCVD Risk calculator in the United States) to guide preventive strategies. Emerging evidence indicates that high-sensitivity cardiac troponin (hsTn) may refine risk stratification.
In vitro blood flow visualizations and cell-free layer (CFL) measurements in a ...
Bento, D.; Fernandes, C. S.; Miranda, J. M.; Lima, Rui Alberto Madeira MacedoMicrovascular networks are not simple straight microchannels but rather complex geometries composed by successive asymmetric divergent and convergent bifurcations. Despite the extensive research work in this field, still lack of knowledge about the blood flow behavior in microvascular networks. The current study applies the most current advanced visualization and microfabrication techniques to provide further i...
CRUSADE: Is it still a good score to predict bleeding inacute coronary syndrome?
Bento, D.; Marques, N.; Guedes, J.; Azevedo, Pedro; Amado, José; Santos, W.; Bispo. J.; Mimoso, J.; Jesus, I.; Silva, D.Introduction: Major bleeding is a serious complication of acute coronary syndrome (ACS) andis associated with a worse prognosis. The CRUSADE bleeding score is used to stratify the risk ofmajor bleeding in ACS.Objective: To assess the predictive ability of the CRUSADE score in a contemporary ACS popu-lation.Methods: In a single-center retrospective study of 2818 patients admitted with ACS, the CRU-SADE score was...
Microbubble moving in blood flow in microchannels: effect on the cell-free laye...
Bento, D.; Sousa, Lúcia; Yaginuma, T.; Garcia, Valdemar; Lima, Rui Alberto Madeira Macedo; Miranda, João M.Gas embolisms can hinder blood flow and lead to occlusion of the vessels and ischemia. Bubbles in microvessels circulate as tubular bubbles (Taylor bubbles) and can be trapped, blocking the normal flow of blood. To understand how Taylor bubbles flow in microcirculation, in particular, how bubbles disturb the blood flow at the scale of blood cells, experiments were performed in microchannels at a low Capillary n...
Wall expansion assessment of an intracranial aneurysm model by a 3D digital ima...
Rodrigues, Raquel O.; Pinho, Diana; Bento, D.; Lima, Rui Alberto Madeira Macedo; Ribeiro, JoãoIntracranial aneurysm is a local dilatation of an intracranial artery with high risk of rupture and death. Although it is generally accepted that the weakening of the arterial wall is the main cause for the rupture of an aneurysm, it still no consensus about the reasons for its creation, expansion and rupture. In particular, what is the role played by the blood flow in these phenomena. In this way, the aim of t...
Screening of Lysosomal acid lipase deficiency in patients with severe dyslipide...
Azevedo, O.; Marques, N.; Antunes, H.; Azevedo, Pedro; Oliveira, M.; Bento, D.; Guedes, J.; Marmelo, B.; Faria, R.; Correia, E.Objectives: To determine the prevalence of Lysosomal Acid Lipase (LAL) deficiency in patients with severe dyslipidemia and premature coronary heart disease.
Computation of a three-dimensional flow in a square microchannel: a comparison ...
Bento, D.; Lima, Rui Alberto Madeira Macedo; Miranda, João M.Traditional grid-based numerical methods, such as finite volume method (FVM), are not suitable to simulate multiphase biofluids (such as blood) at the microscale level. Alternatively, meshfree Lagrangian methods can deal with two or more finely dispersed phases moving relatively to each other. The Moving Particle Semi-Implicit Method (MPS), used in this study, is a deterministic particle method based on a Lagra...
Cell-Free Layer Measurements in a Network with Bifurcating Microchannels Using ...
Bento, D.; Pinho, D.; Pereira, A.I.; Rui Lima