5 documents found, page 1 of 1
Chaves thermal spring water impact on skin health: potential cosmetic application
Pinto-Ribeiro, Inês; Castro, Cláudia; Rocha, Pedro Emanuel; Carvalho, Maria João; Pintado, Ana; Mendes, Adélia; Pedrosa, Sílvia Santos; Capeto, PaulaSince ancient times, thermal spring water has been proven to be beneficial to the skin and to improving dermatologic disorders, explaining its incorporation into cosmetic formulations as an active ingredient. Chaves thermal spring water, from northern Portugal, has been used as a local spa since Roman times, and its customers are satisfied with its medicinal quality. Despite the lack of published evidence on it...
Circular economyeast: saccharomyces cerevisiae as a sustainable source of gluca...
Sousa, Pedro; Tavares-Valente, Diana; Pereira, Carla F.; Pinto-Ribeiro, Inês; Azevedo-Silva, João; Madureira, Raquel; Ramos, Óscar L.; Pintado, ManuelaGlucans, a polysaccharide naturally present in the yeast cell wall that can be obtained from side streams generated during the fermentation process, have gained increasing attention for their potential as a skin ingredient. Therefore, this study focused on the extraction method to isolate and purify water-insoluble glucans from two different Saccharomyces cerevisiae strains: an engineered strain obtained from s...
Cannabidiol and cannabigerol exert antimicrobial activity without compromising ...
Luz-Veiga, Mariana; Amorim, Manuela; Pinto-Ribeiro, Inês; Oliveira, Ana L. S.; Silva, Sara; Pimentel, Lígia L.; Rodríguez-Alcalá, Luís M.Cannabidiol (CBD) and cannabigerol (CBG) are two pharmacologically active phytocannabinoids of Cannabis sativa L. Their antimicrobial activity needs further elucidation, particularly for CBG, as reports on this cannabinoid are scarce. We investigated CBD and CBG’s antimicrobial potential, including their ability to inhibit the formation and cause the removal of biofilms. Our results demonstrate that both molecu...
Impact of a novel sugarcane straw extract-based ingredient on skin microbiota v...
Carvalho, Maria João; Pinto-Ribeiro, Inês; Castro, Cláudia; Pedrosa, Sílvia Santos; Oliveira, Ana L. S.; Pintado, Manuela; Madureira, Ana RaquelDuring cosmetic product development, the impact on the skin microbiota needs to be evaluated, as it plays an important role in skin health. Clinical studies are frequently used to assess cosmetic effects, but are expensive, time-consuming and require finished ingredients, which may be a limiting factor. Thus, this study had two main objectives, the development of a preclinical in vitro model for the evaluation ...
Helicobacter pylori activates matrix metalloproteinase 10 in gastric epithelial...
Costa, Angela M.; Ferreira, Rui M.; Pinto-Ribeiro, Inês; Sougleri, Ioanna S.; Oliveira, Maria J.; Carreto, Laura; Santos, Manuel A.Helicobacter pylori colonizes the human stomach and increases the risk for peptic ulcer disease and gastric carcinoma. H. pylori upregulates the expression and activity of several matrix metalloproteinases (MMPs) in cell lines and in the gastric mucosa. The aim of this study was to explore the mechanisms leading to upregulation of MMP10 in gastric epithelial cells induced by H. pylori Infection of gastric cells...