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Soilless cultivated halophyte plants: volatile, nutritional, phytochemical, and...

Oliveira-Alves, Sheila C.; Andrade, Fábio; Sousa, João; Bento-Silva, Andreia; Duarte, Bernardo; Caçador, Isabel; Salazar, Miguel; Mecha, Elsa

The use of halophyte plants appears as a potential solution for degraded soil, food safety, freshwater scarcity, and coastal area utilization. These plants have been considered an alternative crop soilless agriculture for sustainable use of natural resources. There are few studies carried out with cultivated halophytes using a soilless cultivation system (SCS) that report their nutraceutical value, as well as t...


Improving nutritional quality of unripe tomato through fermentation by a consor...

Simões, Sara; Santos, Rafaela; Bento-Silva, Andreia; Santos, Marisa V.; Mota, Mariana; Duarte, Noélia; Sousa, Isabel; Raymundo, Anabela

BACKGROUND: Portugal is one of the main producers of industrial tomato and tomato paste, an important intermediate ingredient used in many added-value foods. The tomato processing industry rigorously selects the fruits by colour during mechanical harvest, picking only completely ripe fruits to produce high quality tomato paste. The latest available data shows that about 1.12 × 108 kg yr−1 of non-red/not-ripe to...


A newfangled collagenase inhibitor topical formulation based on Ethosomes with ...

Mota, Ana Henriques; Prazeres, Inês; Mestre, Henrique; Bento-Silva, Andreia; Rodrigues, Maria Joao; Duarte, Noélia; Serra, Ana Teresa

Sambucus nigra L. (S. nigra) is a shrub widespread in Europe and western Asia, traditionally used in medicine, that has become popular in recent years as a potential source of a wide range of interesting bioactive compounds. The aim of the present work was to develop a topical S. nigra extract formulation based on ethosomes and thus to support its health claims with scientific evidence. S. nigra extract was pre...


Pyromellitic dianhydride crosslinked soluble cyclodextrin polymers: Synthesis, ...

Adeoye, Oluwatomide; Bártolo, Inês; Conceição, Jaime; Bento-Silva, Andreia; Duarte, Noélia; Francisco, Ana Paula; Taveira, Nuno; Marques, Helena Cabral

We report the synthesis of water soluble cyclodextrin (CD) polymers prepared by crosslinking pyromellitic dianhydride (PMDA) with two CD derivatives (methyl-β-CD - MβCD and (2-hydroxy)propyl-β-CD - HPβCD) and their evaluation as functional sub-micron sized carriers in the development of antiretroviral drug delivery systems. Using the protease inhibitor lopinavir (LPV) as model drug, LPV loaded CD polymers (pHPβ...


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