Objective: To evaluate the potential impacts of low hydration and adequate hydration on clinical signs and symptoms. Materials and Methods: Signs and symptoms of hypersensitivity and constipation were evaluated before and after 40 mL/kg/d of water intake in 24 healthy individuals for 14 days of follow-up. Results: Headache, dizziness, fainting, and insomnia were improved. However, it is worthwhile that no signi...