3 documents found, page 1 of 1
Healing effects of natural latex serum 1% from Hevea brasiliensis in an experim...
Leite,Marcel Nani; Leite,Saulo Nani; Caetano,Guilherme Ferreira; Andrade,Thiago Antônio Moretti de; Fronza,Márcio; Frade,Marco Andrey CiprianiAbstract Background Dermabrasion is related with mechanical and surgical traumas on the skin; usually topical antiseptics and/or saline have been used for healing. Natural products for wound healing can also be used for abrasions, such as latex from Hevea brasiliensis. Objective This study aimed to evaluate the in vitro viability and migratory/proliferative effects of latex serum from H. brasiliensis and to com...
Prolonged viability of human organotypic skin explant in culture method (hOSEC)
Frade,Marco Andrey Cipriani; Andrade,Thiago Antônio Moretti de; Aguiar,Andréia Fernanda Carvalho Leone; Guedes,Flávia Araújo; Leite,Marcel NaniAbstract BACKGROUND: Currently, the cosmetic industry is overwhelmed in keeping up with the safety assessment of the increasing number of new products entering the market. To meet such demand, research centers have explored alternative methods to animal testing and also the large number of volunteers necessary for preclinical and clinical tests. OBJECTIVES: This work describes the human skin ex-vivo model (hOSE...
Phototherapy promotes healing of cutaneous wounds in undernourished rats
Leite,Saulo Nani; Andrade,Thiago Antônio Moretti de; Masson-Meyers,Daniela dos Santos; Leite,Marcel Nani; Enwemeka,Chukuka S.BACKGROUND: Various studies have shown that phototherapy promotes the healing of cutaneous wounds. OBJECTIVE: To investigate the effect of phototherapy on healing of cutaneous wounds in nourished and undernourished rats. METHODS: Forty rats, 20 nourished plus 20 others rendered marasmus with undernourishment, were assigned to four equal groups: nourished sham, nourished Light Emitting Diode treated, undernouris...