8 documents found, page 1 of 1

Differences in the volatilomic urinary biosignature of prostate cancer patients...

<jats:p>Prostate cancer (PCa) continues to be the second most common malignant tumour and the main cause of oncological death in men. Investigating endogenous volatile organic metabolites (VOMs) produced by various metabolic pathways is emerging as a novel, effective, and non-invasive source of information to establish the volatilomic biosignature of PCa. In this study, headspace solid-phase microextraction com...

P- CANCER AMONG ELDERLY:A 10-YEAR CHARACTERIZATION OF CASES FROM THE MADEIRA AR...

The evolution of science and improvement of medicine led to the extension of life expectancy resulting in a higher number of elder people among population.Consequently, life expectancy also increases diseases, such as cancer, one of the main causes of morbidity and mortality worldwide.In Portugal, cancer is the second leading cause of mortality, accounting for about 1/4 of deaths. With this work, it is intended...

P- Neoadjuvant Chemoradiotherapy as an Improved Prognostic Over rectal Cancer P...

Registo Oncológico na Região, 2018

Introdução : Em 2018, foram identificados na RAM 1410 novos casos de doenças oncológicas. Destes, 1159 corresponderam a casos de tumores malignos que foram incluídos na análise estatística principal. A exclusão de carcinomas da pele não melanoma (tipo basocelular, espinocelular, não especificados e outros) realiza-se de modo a ser possível a comparação com outros dados estatísticos nacionais e internacionais. A...

Exploring the potential of a MEPS/UHPLC-based methodology on the Exploring the ...

Asthma is a heterogeneous disease characterized by chronic inflammation and long term irreversible remodeling of the airways. The enzymatic peroxidation of the arachidonic acid is part of the pathophysiology of this disease and leads to the formation of powerful inflammatory mediators, characteristic of asthma. The present work aimed to develop an easy-to-use ultra-high pressure liquid chromatography (UHPLC)-ba...

Determination of potential childhood asthma biomarkers using a powerful methodo...

Leukotrienes and prostaglandins are arachidonic acid bioactive derived eicosanoids and key mediators of bronchial inflammation and response modulation in the airways contributing to the pathophysiology of asthma. An easy-to-use ultra-high pressure liquid chromatography (UHPLC)-based strategy was developed to characterize biomarkers of lipid peroxidation: leukotrienes E (LTE4) and B4 (LTB4) and 11β-prostaglandin...

Exploring a volatomic-based strategy for a fingerprinting approach of Vaccinium...

The effect of ripening on the evolution of the volatomic pattern from endemic Vaccinium padifolium L. (Uveira) berries was investigated using headspace-solid phase microextraction (HS-SPME) followed by gas chromato graphy/quadrupole-mass spectrometry (GC–qMS) and multivariate statistical analysis (MVA). The most sig nificant HS-SPME parameters, namely fibre polymer, ionic strength and extraction time, were opti...

Madeira-a tourist destination for asthma sufferers

Madeira Island is a famous tourist destination due to its natural and climatic values. Taking into account optimal weather conditions, flora richness and access to various substrates facilitating fungal growth, we hypothesised a very high risk of elevated fungal spore and pollen grain concentrations in the air of Funchal, the capital of Madeira. Concentration levels of the most allergenic taxa were measured fro...